Ethnic differences in responses to multiple experimental pain stimuli
Ethnic differences in responses to multiple experimental pain stimuli
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DOI：
10.1016/j.pain.2004.08.013
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发表时间：
2005-01-01
期刊：
影响因子：
7.4
通讯作者：
Fillingim, RB
中科院分区：
文献类型：
--
作者：
Campbell, CM;Edward, RR;Fillingim, RB
越来越多的文献表明，临床疼痛的经验不同的民族文化群体。此外，一些证据表明非裔美国人对实验性疼痛更敏感：然而，大多数研究仅包括一种疼痛方式。本研究探讨了种族差异的反应，多种实验疼痛刺激，包括热痛，冷加压疼痛，缺血性疼痛。在120名（62名非洲裔美国人，58名白色）健康年轻人中评估了热痛阈值和耐受性、重复阈上热评级、缺血性和冷加压痛阈值和耐受性。此外，还使用了几种心理工具。阈值测量没有种族差异，但与白人相比，非洲裔美国人对热痛、冷加压痛和缺血性疼痛的耐受性较低。在非裔美国人中，阈上热刺激的强度和不愉快的评分显着较高。非裔美国人报告更多地使用被动疼痛应对策略和更高水平的高度警惕。控制被动疼痛应对并不能解释疼痛反应的组间差异，而控制过度警觉则使热痛耐受性和缺血性疼痛耐受性的组间差异不显著。这些研究结果表明，在实验室疼痛反应之间的差异，非洲裔美国人和白人之间的多种刺激方式，和这些差异的疼痛耐受性的影响大小是中度至大的阈上措施。过度警惕部分解释了组间差异。需要进一步研究以确定这些影响的机制。(C)2004年国际疼痛研究协会。Elsevier B.V.出版，保留所有权利。
A growing body of literature suggests that the experience of clinical pain differs across ethnocultural groups. Additionally, some evidence indicates greater sensitivity to experimentally induced pain among African Americans: however, most studies have included only one pain modality. This study examined ethnic differences in responses to multiple experimental pain stimuli, including heat pain, cold pressor pain, and ischemic pain. Heat pain threshold and tolerance, ratings of repetitive suprathreshold heat, and ischemic and cold pressor pain threshold and tolerance were assessed in 120 (62 African American, 58 white) healthy young adults. Also, several psychological instruments were administered. No ethnic group differences emerged for threshold measures, but African Americans had lower tolerances for heat pain, cold pressor pain and ischemic pain compared to whites. Ratings of intensity and unpleasantness for suprathreshold heat stimuli were significantly higher among African Americans. African Americans reported greater use of passive pain coping strategies and higher levels of hypervigilance. Controlling for passive pain coping did not account for group differences in pain responses, while controlling for hypervigilance rendered group differences in heat pain tolerance and ischemic pain tolerance non-significant. These findings demonstrate differences in laboratory pain responses between African Americans and whites across multiple stimulus modalities, and effect sizes for these differences in pain tolerance were moderate to large for suprathreshold measures. Hypervigilance partly accounted for group differences. Additional research to determine the mechanisms underlying these effects is warranted. (C) 2004 International Association for the Study of Pain. Published by Elsevier B.V. All rights reserved.