Differential neural coding of acoustic flutter within primate auditory cortex
Differential neural coding of acoustic flutter within primate auditory cortex
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DOI：
10.1038/nn1888
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发表时间：
2007-06-01
影响因子：
25
通讯作者：
Wang, Xiaoqin
中科院分区：
文献类型：
--
作者：
Bendor, Daniel;Wang, Xiaoqin
声事件序列被感知为一个连续的声音或作为一个时间离散的声音流（声颤），这取决于声事件重复的速率。听觉颤动是以接近或低于感知音高的下限的重复率感知的，并且类似于由感官刺激的缓慢重复引起的视觉闪烁和触觉颤动的离散感知。研究表明，在初级听觉皮层（AI）中，缓慢重复的声事件可以由刺激同步的神经元放电模式明确表示。在这里，我们表明，第二个神经代码的声扑存在于听觉皮层的绒猴（Callithrix jacchus），其中的神经元的发射率是一个单调的函数的声学事件的重复率。而AI中的许多神经元编码声扑使用双时间/速率表示，我们发现，在皮层领域的神经元喙AI主要使用单调的速率代码和缺乏刺激同步放电。这些结果表明，声扑的神经表征是沿着听皮层的尾侧-吻侧轴沿着转换的。
A sequence of acoustic events is perceived either as one continuous sound or as a stream of temporally discrete sounds (acoustic flutter), depending on the rate at which the acoustic events repeat. Acoustic flutter is perceived at repetition rates near or below the lower limit for perceiving pitch, and is akin to the discrete percepts of visual flicker and tactile flutter caused by the slow repetition of sensory stimulation. It has been shown that slowly repeating acoustic events are represented explicitly by stimulus-synchronized neuronal firing patterns in primary auditory cortex (AI). Here we show that a second neural code for acoustic flutter exists in the auditory cortex of marmoset monkeys (Callithrix jacchus), in which the firing rate of a neuron is a monotonic function of an acoustic event's repetition rate. Whereas many neurons in AI encode acoustic flutter using a dual temporal/rate representation, we find that neurons in cortical fields rostral to AI predominantly use a monotonic rate code and lack stimulus-synchronized discharges. These findings indicate that the neural representation of acoustic flutter is transformed along the caudal-to-rostral axis of auditory cortex.