Herd and individual animal risks associated with bovine tuberculosis skin test positivity in cattle in herds in south west England
Herd and individual animal risks associated with bovine tuberculosis skin test positivity in cattle in herds in south west England
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DOI：
10.1016/j.prevetmed.2009.08.011
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发表时间：
2009-11-15
影响因子：
2.6
通讯作者：
Green, L. E.
中科院分区：
文献类型：
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作者：
Ramirez-Villaescusa, A. M.;Medley, G. F.;Green, L. E.
本研究的目的是调查与整群牛结核病（bTB）皮肤试验中牛动物反应风险相关的牛暴露因素。共有148个研究农场入组。这些农场位于英格兰西南部的六个县，被认为是牛结核病（bTB）的地方病：24%在2001年口蹄疫（FMD）后重新放养;所有农场都位于随机獾扑杀试验（RBCT）区域内。这些农场的牛的数据来自1996年至2004年的bTB Vetnet数据库和英国牛运动计划数据库。创建了个体动物记录，其中包括以下数据：2001年6月1日至2004年8月19日期间动物是否在全牛群bTB试验中成为反应者、其既往暴露于bTB牛（定义为在bTB试验中存在，其中至少检测到一种反应者）、动物是否为家养动物、bTB农场历史和农场重新放养状态。使用了来自144个农场的数据，4个农场没有数据。当牛参加过先前的bTB牛群试验（或试验）时，其他牛对皮肤试验有反应时，牛更有可能对bTB皮肤试验有反应。这与动物的年龄和bTB测试次数呈正相关。与持续放养的农场的牛相比，重新放养的农场的牛对皮肤试验的反应可能性较小。这些结果突出表明，在先前的试验中暴露于受感染的牛可能是随后成为反应者的牛的感染源，并表明新形成的牛群中牛暴露于bTB的风险较低。(C)2009 Elsevier B. V.保留所有权利。
The aim of this study was to investigate the cattle-exposure factors associated with the risk of a bovine animal reacting to a bovine tuberculosis (bTB) skin test at a whole herd test. There were 148 study farms enrolled. These were located in six counties of the south west of England in an area considered endemic for bovine tuberculosis (bTB): 24% were restocked after foot and mouth disease (FMD) in 2001; all farms were located within the Randomised Badger Culling Trial (RBCT) area. Data on cattle on these farms were sourced from the bTB Vetnet database from 1996 to 2004 and from the British Cattle Movement Scheme database. Individual animal records were created that included data on whether or not an animal became a reactor at a full-herd bTB test between 1 June 2001 and 19 August 2004, their prior exposure to cattle with bTB (defined by presence at a bTB test where at least one reactor was detected), whether the animal was homebred, the farm history of bTB and the farm restocking status. Data from 144 farms were used, 4 farms had no data. Cattle were more likely to react to the bTB skin test when they had been present at a previous bTB herd test (or tests) where other cattle had reacted to the skin test. This positively correlated with age and the number of bTB tests an animal had had. Cattle on restocked farms were less likely to react to the skin test compared with cattle on continuously stocked farms. These results highlight the likely importance of exposure to infected cattle at a previous test as a source of infection to cattle that subsequently became reactors and suggest that there was a lower risk of exposure to bTB to cattle in newly formed herds. (C) 2009 Elsevier B.V. All rights reserved.