Functional Neuroanatomy and Neurophysiology of Functional Neurological Disorders (Conversion Disorder).

Functional Neuroanatomy and Neurophysiology of Functional Neurological Disorders (Conversion Disorder).
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功能性神经疾病(转换障碍)的功能神经解剖学和神经生理学。

DOI:
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发表时间:
2016
期刊:
The Journal of Neuropsychiatry and Clinical Neurosciences
影响因子:
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通讯作者:
W. C. LaFrance
W. C. LaFrance
中科院分区:
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文献类型:
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作者:
Valerie Voon;Valerie Voon;A. Cavanna;A. Cavanna;K. Coburn;S. Sampson;A. Reeve;W. C. LaFrance

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关于功能性神经障碍(FND)/转换障碍患者的身体特征、共病症状、心理构成和神经心理学表现,人们已经了解很多。严重的神经结构缺陷不能解释患者的缺陷或症状。本综述描述了关注 FND 个体潜在神经生物学(即功能性神经解剖学/神经生理学)发现的文献,检查了各种形式的运动和感觉 FND 患者的神经影像学和神经生理学研究。总之,神经网络和神经生理学机制可能介导“功能性”症状,反映神经生物学和心理过程。
Much is known regarding the physical characteristics, comorbid symptoms, psychological makeup, and neuropsychological performance of patients with functional neurological disorders (FNDs)/conversion disorders. Gross neurostructural deficits do not account for the patients' deficits or symptoms. This review describes the literature focusing on potential neurobiological (i.e. functional neuroanatomic/neurophysiological) findings among individuals with FND, examining neuroimaging and neurophysiological studies of patients with the various forms of motor and sensory FND. In summary, neural networks and neurophysiologic mechanisms may mediate "functional" symptoms, reflecting neurobiological and intrapsychic processes.
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