Prospective relationships of physical activity with quality of life among colorectal cancer survivors
Prospective relationships of physical activity with quality of life among colorectal cancer survivors
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DOI：
10.1200/jco.2007.15.7917
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发表时间：
2008-09-20
影响因子：
45.3
通讯作者：
Aitken, Joanne F.
中科院分区：
文献类型：
--
作者：
Lynch, Brigid M.;Cerin, Ester;Aitken, Joanne F.
目的：体育锻炼可以提高癌症幸存者的生活质量。然而，很少有纵向研究探讨体育活动是否对生活质量的改善有持续的影响。本研究的目的是探讨身体活动和生活质量之间的关系超过2年后，结直肠癌diagnosis.Patients and MethodsData内收集的结直肠癌和生活质量的研究，其中1,966人诊断为结直肠癌招募通过昆士兰州癌症登记。参与者在诊断后约6个月，12个月和24个月完成电话采访。广义线性混合模型被用来估计的整体，个体间，和个体内水平的独立影响，参与体力活动对生活quality of life.ResultsThere是一个整体的体力活动和生活质量之间的独立关联。在给定的时间点，每周至少进行150分钟体力活动的参与者的生活质量评分比那些没有进行体力活动的人高出18%。显着的协会也存在于个体间水平（参与者之间的差异）和个体内水平（参与者的变化）。ConclusionThese研究结果表明，身体活动和生活质量之间的正相关是一致的，随着时间的推移。鼓励结直肠癌幸存者进行身体活动可能是提高生活质量的一种有益策略。
PurposePhysical activity can enhance quality of life for cancer survivors. However, few longitudinal studies have examined whether physical activity has a sustained effect on improvements in quality of life. The present study aims to examine the relationships between physical activity and quality of life over 2 years after a colorectal cancer diagnosis.Patients and MethodsData were collected within the Colorectal Cancer and Quality of Life Study, in which 1,966 people diagnosed with colorectal cancer were recruited through the Queensland Cancer Registry. Participants completed telephone interviews at approximately 6, 12, and 24 months after diagnosis. Generalized linear mixed models were used to estimate the overall, interindividual, and intraindividual level independent effects of participation in physical activity on quality of life.ResultsThere was an overall independent association between physical activity and quality of life. At a given time point, participants achieving at least 150 minutes of physical activity per week had an 18% higher quality of life score than those who reported no physical activity. Significant associations were also present at the interindividual level (differences between participants) and intraindividual level (within participant changes).ConclusionThese findings suggest that the positive association between physical activity and quality of life is consistent over time. Encouraging colorectal cancer survivors to be physically active may be a helpful strategy for enhancing quality of life.