Stability of formal thought disorder and referential communication disturbances in schizophrenia
Stability of formal thought disorder and referential communication disturbances in schizophrenia
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DOI：
10.1037/0021-843x.112.3.469
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发表时间：
2003-08-01
影响因子：
4.6
通讯作者：
Dangelmaier, RE
中科院分区：
文献类型：
--
作者：
Docherty, NM;Cohen, AS;Dangelmaier, RE
本研究探讨在何种程度上不同类型的沟通障碍，在言语中的48例精神分裂症患者和28名对照变量和状态相关与稳定和traitlike。临床评定的正式思维障碍和5种类型的参照障碍显示，随着时间的推移，参与者基本稳定。第六种参照障碍，即模糊参照，随着时间的推移并不稳定。正式思维障碍与患者的核心精神病性症状的严重程度相关，而参照障碍与阳性或阴性症状的严重程度几乎没有相关性。此外，随着时间的推移，精神病症状的变化伴随着相应的变化，在正式的思维障碍，但不参考障碍。这些结果支持了这样的想法，某些类型的参照干扰是traitlike的，可能是反映的脆弱性，以及明显的疾病。
This study examined the degree to which different types of communication disturbances in the speech of 48 schizophrenia patients and 28 controls were variable and state related versus stable and traitlike. Clinically rated formal thought disorder and 5 types of referential disturbance showed substantial stability within participants over time. The sixth type of referential disturbance, the vague reference, was not stable over time. Formal thought disorder was associated with the severity of core psychotic symptoms in patients, whereas referential disturbances showed little or no association with positive or negative symptom severity. Furthermore, changes in psychotic symptoms over time were accompanied by corresponding changes in formal thought disorder but not referential disturbances. These results support the idea that some types of referential disturbances are traitlike and may be reflective of vulnerability as well as manifest illness.