Substantial effect of Cr doping on the antimicrobial activity of ZnO nanoparticles prepared by ultrasonication process
Substantial effect of Cr doping on the antimicrobial activity of ZnO nanoparticles prepared by ultrasonication process
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Cr掺杂对超声法制备的ZnO纳米颗粒抗菌活性的显着影响
DOI：
10.1016/j.mseb.2020.114817
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发表时间：
2021-01-01
影响因子：
3.6
通讯作者：
Li, Wen-Jun
中科院分区：
文献类型：
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作者：
Rajivgandhi, Govindan Nadar;Ramachandran, Govindan;Li, Wen-Jun
研究了Cr掺杂对ZnO纳米粉体的结构、形貌、光学性能和抗菌性能的影响。X射线衍射分析表明，合成的粉体为六方纤锌矿结构，晶粒尺寸减小。扫描电子显微镜（SEM）结果证实，在Cr掺杂的ZnO纳米颗粒上观察到六方形状的颗粒的形成。在450-600 cm（-1）范围内的振动带的存在被证实，在裸的和Cr掺杂的ZnO纳米颗粒中成功地形成了Zn-O键。紫外-可见漫反射光谱中的反射率降低和红移证实了带隙能量的降低。纳米粉体的抑菌实验表明，纳米粉体对K.肺炎衣原体和C.与其他微生物相比。因此，Cr掺杂ZnO纳米粒子有望成为开发新型抗菌药物的候选材料。
This study was involved to investigate the effect of Cr incorporation on various physic-chemical properties of ZnO nanopowder that including structural, morphological, optical and antibacterial. The synthesized powder reveals wurtzite hexagonal structure with decreased crystallite size from X-ray diffraction analysis. The scanning electron microscope (SEM) result confirmed that the formation of hexagonal shaped particles was observed on Cr doped ZnO nanoparticles. The presence of vibration band in the range of 450-600 cm(-1) was confirm, the successful formation of Zn-O bond in bare and Cr doped ZnO nanoparticles. The decreased reflectance and red shift in the UV-vis diffused reflectance spectra was confirmed the decreased band gap energy. The antibacterial investigation of the nanopowder reveals, the higher zone of inhibition, membrane damage and intracellular alterations were observed against K. pneumoniae and C. albicans compared with other microorganisms. Thus, the result was suggested that the Cr doped ZnO nanoparticle as a promising candidate material for the development of new antibiotics against various bacteria.