Biocompatible polymer enhances the in vitro and in vivo transfection efficiency of HVJ envelope vector
Biocompatible polymer enhances the in vitro and in vivo transfection efficiency of HVJ envelope vector
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DOI：
10.1002/jgm.735
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发表时间：
2005-07
期刊：
影响因子：
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通讯作者：
Hidetoshi Mima;Ryuji Tomoshige;Toshihide Kanamori;Y. Tabata;Seiji Yamamoto;S. Ito;K. Tamai;Y. Kaneda
中科院分区：
文献类型：
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作者：
Hidetoshi Mima;Ryuji Tomoshige;Toshihide Kanamori;Y. Tabata;Seiji Yamamoto;S. Ito;K. Tamai;Y. Kaneda
载体的开发对于人类基因治疗的进展至关重要。然而，病毒载体的使用引起了许多安全性问题，并且大多数非病毒方法对于基因转移效率较低。载体技术的突破之一是载体与各种聚合物的结合。
Vector development is critical for the advancement of human gene therapy. However, the use of viral vectors raises many safety concerns and most non‐viral methods are less efficient for gene transfer. One of the breakthroughs in vector technology is the combination of the vector with various polymers.