Prenylated diphenyl ethers from the mantis-associated fungus Aspergillus versicolor GH-2

Prenylated diphenyl ethers from the mantis-associated fungus Aspergillus versicolor GH-2
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来自螳螂相关真菌 Aspergillus versicolor GH-2 的异戊二烯化二苯醚

DOI:
10.1016/j.tetlet.2015.04.109
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发表时间:
2015-06-17
影响因子:
1.8
通讯作者:
Jiao, Rui-hua
Jiao, Rui-hua
中科院分区:
化学4区
文献类型:
--
作者:
Hu, Sha-sha;Jiang, Nan;Jiao, Rui-hua

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从螳蛄相关真菌Aspergillus versicolor GH-2中分离得到5个新戊基二苯醚(1-5)、5个已知二苯醚(6-10)、3个口山酮(11-13)和3个蒽醌衍生物(14-16)。利用光谱学方法对其结构进行了分析。用改进的Mosher酯法确定了1的(2”S)绝对构型。已知化合物9和12对临床病原菌化脓性链球菌的MIC值分别为2.5和5.0 μ g/mL。(C) 2015 Elsevier Ltd.版权所有。
Five new prenylated diphenyl ethers (1-5), five known ones (6-10), and three xanthones (11-13), together with three anthraquinone derivatives (14-16), were obtained from the mantis-associated fungus Aspergillus versicolor GH-2. Their structures were elucidated on the basis of spectroscopic methods. The (2 '' S) absolute configuration of 1 was assigned by using the modified Mosher ester method. The known compounds 9 and 12 exhibited antibacterial activity against the clinical strain Streptococcus pyogenes with the MIC values of 2.5 and 5.0 mu g/mL, respectively. (C) 2015 Elsevier Ltd. All rights reserved.