Rigidity of melting DNA
Rigidity of melting DNA
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DOI：
10.1103/physreve.93.052102
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发表时间：
2016-05-02
影响因子：
2.4
通讯作者：
Bhattacharjee, Somendra M.
中科院分区：
文献类型：
--
作者：
Pal, Tanmoy;Bhattacharjee, Somendra M.
研究了在拉伸力和解压缩力存在下DNA柔性的温度依赖性。考虑两类模型。在一种情况下，弹性的起源是熵，由于聚合物的相关性，而在另一种情况下，双链DNA被认为具有弯曲的固有刚性。在这两种情况下，单链都是完全柔性的。由于热产生的气泡的弹性常数的变化的灵活的情况下，准确地获得。对于内禀刚性的情况下，弹性常数被发现是成正比的气泡数波动的平方根。
The temperature dependence of DNA flexibility is studied in the presence of stretching and unzipping forces. Two classes of models are considered. In one case the origin of elasticity is entropic due to the polymeric correlations, and in the other the double-stranded DNA is taken to have an intrinsic rigidity for bending. In both cases single strands are completely flexible. The change in the elastic constant for the flexible case due to thermally generated bubbles is obtained exactly. For the case of intrinsic rigidity, the elastic constant is found to be proportional to the square root of the bubble number fluctuation.