Phytanic acid alpha-oxidation in human cultured skin fibroblasts.
Phytanic acid alpha-oxidation in human cultured skin fibroblasts.
复制标题
人类培养的皮肤成纤维细胞中植烷酸的α-氧化。
DOI：
10.1016/0925-4439(92)90072-u
复制
发表时间：
1992
期刊：
影响因子：
--
通讯作者：
Singh,AK
中科院分区：
文献类型：
--
作者：
Singh,I;Lazo,O;Kalipada,P;Singh,AK
We studied the oxidation of [1-14C]phytanic acid, 3-methyl substituted fatty acid, to pristanic acid and14CO2in human skin fibroblasts. The specific activity for α-oxidation of phytanic acid in peroxisomes was 29- and 124-fold higher than mitochondria and endoplasmic reticulum. This finding demonstrates for the first time the presence of fatty acid α-oxidation enzyme system in peroxisomes.
