Optimal control of coupled spin dynamics:: design of NMR pulse sequences by gradient ascent algorithms
Optimal control of coupled spin dynamics:: design of NMR pulse sequences by gradient ascent algorithms
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DOI：
10.1016/j.jmr.2004.11.004
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发表时间：
2005-02-01
影响因子：
2.2
通讯作者：
Glaser, SJ
中科院分区：
文献类型：
--
作者：
Khaneja, N;Reiss, T;Glaser, SJ
本文介绍了核磁共振波谱中脉冲序列设计的最优控制算法。该方法用于设计脉冲序列，以在给定的指定时间内最大化耦合自旋之间的相干转移，最小化给定相干转移步骤中的松弛效应或最小化产生给定酉传播子所需的时间。这些脉冲工程方法的应用，以设计脉冲序列是鲁棒的实验重要的参数变化，如化学位移色散或射频（rf）的变化，由于射频不均匀性等缺陷也解释了。(C) 2004爱思唯尔公司版权所有。
In this paper, we introduce optimal control algorithm for the design of pulse sequences in NMR spectroscopy. This methodology is used for designing pulse sequences that maximize the coherence transfer between coupled spins in a given specified time, minimize the relaxation effects in a given coherence transfer step or minimize the time required to produce a given unitary propagator, as desired. The application of these pulse engineering methods to design pulse sequences that are robust to experimentally important parameter variations, such as chemical shift dispersion or radiofrequency (rf) variations due to imperfections such as rf inhomogeneity is also explained. (C) 2004 Elsevier Inc. All rights reserved.