Enhanced vector competence of Aedes aegypti (Diptera:Culicidae) from the torres strait compared with mainland Australia for dengue 2 and 4 viruses
Enhanced vector competence of Aedes aegypti (Diptera:Culicidae) from the torres strait compared with mainland Australia for dengue 2 and 4 viruses
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DOI：
10.1603/0022-2585-40.6.950
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发表时间：
2003-11-01
影响因子：
2.1
通讯作者：
Ryan, PA
中科院分区：
文献类型：
--
作者：
Knox, TB;Kay, BH;Ryan, PA
澳大利亚埃及伊蚊Aedes Aegypti(L.)来自托雷斯海峡和三个大陆地区(查特斯塔、汤斯维尔和凯恩斯)的蚊子以含有登革2型病毒(DEN-2)或登革病毒4型(DEN-4)的血液悬浮液喂养。Ae对DEN-2(59-99%)和DEN-4(28-79%)的口腔易感性存在变异。埃及伊蚊在摄入感染血液后第8、12、16或20天进行病毒检测。托雷斯海峡Ae.埃及伊蚊对DEN-2最敏感，在16d时向毛细管内传播的效率显著高于大陆Ae(76%)。埃及伊蚊种群(20-28%传播)。托雷斯海峡Ae.埃及伊蚊也是最容易感染DEN-4的，尽管在16d(12%对0-4%)或20d(16%对4-16%)的传播与大陆人群没有显著差异。DEN-2或DEN-4的播散性感染(即腿部感染)并不能准确预测传播潜力。这项研究显示了澳大利亚Ae之间的差异。埃及伊蚊种群对DEN-2和DEN-4的媒介能力。托雷斯海峡Ae.埃及伊蚊的感染频率更高，能够以更高的速度传播DEN-2病毒。这些数据表明，托雷斯海峡地区可能比大陆地区更容易接受登革热传播，这一发现与以往的疫情有关。
Australian Aedes aegypti (L.) mosquitoes colonized from the Torres Strait and three mainland localities (Charters Towers, Townsville, and Cairns) were fed on blood suspensions containing dengue virus type 2 (DEN-2) or dengue virus type 4 (DEN-4). Variation was found in oral susceptibility to DEN-2 (59-99% infection) and DEN-4 (28-79% infection) among Ae. aegypti assayed for virus at 8, 12, 16, or 20 d after ingestion of infected blood. Torres Strait Ae. aegypti were the most susceptible to DEN-2 and were significantly more efficient in transmission to capillary tube at 16 d (76% transmission) than mainland Ae. aegypti populations (20-28% transmission). Torres Strait Ae. aegypti were also the most susceptible to DEN-4, although transmission did not vary significantly from mainland populations at 16 d (12% compared with 0-4%) or 20 d (16% compared with 4-16%). Disseminated infection (i.e., leg infection) with either DEN-2 or DEN-4 was not an accurate predictor of transmission potential. This study demonstrates differences among Australian Ae. aegypti populations in vector competence for DEN-2 and DEN-4. Torres Strait Ae. aegypti were more frequently infected and able to transmit DEN-2 at higher rates than mainland populations. These data indicate that the Torres Strait region is potentially more receptive to dengue transmission than mainland localities, a finding discussed with respect to past outbreaks.