White‐light endoscopy is insufficient to distinguish between types of esophageal white lesions
White‐light endoscopy is insufficient to distinguish between types of esophageal white lesions
复制标题
白光内窥镜不足以区分食管白色病变的类型
DOI：
10.1111/1751-2980.13039
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发表时间：
2021-08
影响因子：
3.5
通讯作者：
Ying-Lian Xiao
中科院分区：
文献类型：
--
作者：
Nian-di Tan;Yu-Qing Lin;Zi-Yin Ye;Ning Zhang;Song-Feng Chen;Meng-Yu Zhang;Yi Cui;Min-Hu Chen;Ying-Lian Xiao
食管白色病变（EWL）是上消化道内镜下常见的病变，但其临床意义尚未确定。本研究的目的是确定EWL的内镜特征，并区分不同类型的EWL.MethodsConsequently患者上消化道投诉和参与者承认健康检查谁接受了食管胃镜检查，从2018年10月至2019年8月在三级医院进行了前瞻性筛选。内镜下检测EWL，并进行组织学分析。结果在3641例连续筛查的受试者中，303例（56.12 ± 10.95岁）有EWL，检出率为8.3%。超过三分之一的人喜欢喝热饮，吃腌制或辛辣食物，吸烟和饮酒，5.3%的人患有当前或以前的上消化道或头颈部癌症。EWL的常见内镜外观（直径为2.9 mm ± 1.2 mm）包括轻微隆起的斑块，颜色为半透明的白色，边界清晰，形状为圆形或椭圆形，表面粗糙或光滑。组织学显示13例轻度上皮内异型增生，10例白斑，1例肠上皮化生。EWL的组织学表现和内镜表现之间无显着差异。结论EWL在日常内镜检查中并不少见，其中一些是癌前病变。传统的白色光内镜不足以识别EWL，而组织学评估很重要。需要使用先进的内窥镜技术进行进一步研究并进行长期随访。
ObjectiveEsophageal white lesions (EWL) are commonly observed under upper endoscopy, while their clinical significance remains undetermined. The aim of this study was to identify the endoscopic characteristics of EWL and distinguish between different types of EWL.MethodsConsecutive patients with upper gastrointestinal complaints and participants admitted for health check‐up who underwent esophagogastroduodenoscopy from October 2018 to August 2019 in a tertiary hospital were prospectively screened. EWL were detected under endoscopy and biopsy was performed for histological analysis. Participants' characteristics, lifestyle, esophageal motility and reflux monitoring variables were analyzed.ResultsOf the 3641 consecutive participants screened, 303 of them aged 56.12 ± 10.95 years were found to have EWL (detection rate of 8.3%). More than one‐third of them preferred hot drinks, eating pickled or spicy food, smoking and alcohol consumption and 5.3% had current or former upper gastrointestinal or head and neck cancers. The common endoscopic appearance of the EWL (2.9 mm ± 1.2 mm in diameter) included slightly elevated plaque, translucent white in color, with a clear border, round or oval in shape, and a scaly, rough or smooth surface. Histology showed low‐grade intraepithelial dysplasia in 13 cases, leukoplakia in 10 and intestinal metaplasia in one. No significant differences were found between the histological findings and endoscopic manifestations of EWL.ConclusionsEWL are not uncommon in daily endoscopic examination, with some of them being precancerous lesions. Conventional white‐light endoscopy is insufficient to identify EWL, while histological assessment is important. Further studies using advanced endoscopic techniques with long‐term follow‐up are needed.
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影响因子：
24.5
作者：
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通讯作者：
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通讯作者：
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