Real-time imaging of two-dimensional cardiac strain using a harmonic phase magnetic resonance imaging (HARP-MRI) pulse sequence
Real-time imaging of two-dimensional cardiac strain using a harmonic phase magnetic resonance imaging (HARP-MRI) pulse sequence
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DOI：
10.1002/mrm.10509
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发表时间：
2003-07-01
影响因子：
3.3
通讯作者：
Prince, JL
中科院分区：
文献类型：
--
作者：
Sampath, S;Derbyshire, JA;Prince, JL
谐波相位（HARP）方法提供了标记的磁共振（MR）图像的自动和快速分析，用于心肌应变的量化和可视化。在这篇文章中，开发和实施的脉冲序列，获取HARP图像在真实的时间进行了说明。在该脉冲序列中，在每个心动周期期间采集具有1-1磁化空间调制（SPAMM）标签的CINE图像序列，在连续心跳中在垂直和水平标签之间交替。成像RF翻转角的递增序列用于补偿由于T-1弛豫和所施加的成像脉冲两者引起的谐波峰值的衰减。显示粗略解剖结构的幅值图像在每次心跳后自动重建并以真实的时间显示。HARP应变图像以每秒四幅图像的速度离线生成;实时处理应该可以使用更快的算法或计算机。本文比较了正常人无屏气和屏气实验中心肌收缩力的变化。(C)2003 Wiley-Liss，Inc.
The harmonic phase (HARP) method provides automatic and rapid analysis of tagged magnetic resonance (MR) images for quantification and visualization of myocardial strain. In this article, the development and implementation of a pulse sequence that acquires HARP images in real time are described. In this pulse sequence, a CINE sequence of images with 1-1 spatial modulation of magnetization (SPAMM) tags are acquired during each cardiac cycle, alternating between vertical and horizontal tags in successive heartbeats. An incrementing train of imaging RF flip angles is used to compensate for the decay of the harmonic peaks due to both T-1 relaxation and the applied imaging pulses. The magnitude images displaying coarse anatomy are automatically reconstructed and displayed in real time after each heartbeat. HARP strain images are generated off line at a rate of four images per second; real-time processing should be possible with faster algorithms or computers. A comparison of myocardial contractility in non-breath-hold and breath-hold experiments in normal humans is presented. (C) 2003 Wiley-Liss, Inc.