Relationship betweenrefraction and allergic conjunctivitis
Relationship betweenrefraction and allergic conjunctivitis
复制标题
屈光与过敏性结膜炎的关系
作者：
Mimura T;Mimura Y;Arimoto A;Amano S;Yamagami S;Funatsu H;Usui T;Noma H;Honda N;Okamoto S
目的外源性过敏原是过敏性疾病发病的主要致病因素；然而，人们对眼睛的生物结构等内部因素知之甚少。我们调查了屈光不正和过敏性结膜炎之间的关系，以揭示1015名受试者的发病机制。方法将患者分为伴变应性结膜炎的隐形眼镜患者（73例）、无变应性结膜炎的隐形眼镜患者（59例）、伴变应性结膜炎的非隐形眼镜患者（224例）和无过敏性结膜炎的非隐形眼镜患者（659例）。测量所有受试者的球形度数、圆柱形度数、角膜半径、最小和最大角膜屈光度。结果在非配戴隐形眼镜的患者中，变应性结膜炎患者的球等效和球功率显著低于非变应性结膜炎患者（- 3.01±3.83 D vs - 1.36±3.08 D， P< 0.0001; - 2.64±3.63 D vs - 1.05±2.88 D， P< 0.0001），而配戴隐形眼镜的患者与非变应性结膜炎患者的各项参数均无显著差异。结论
PurposeExternal allergens are the main causative factor in the pathogenesis of allergic diseases; however, little is known about internal factors such as the biometrical structure of the eye. We investigated the relationship between refractive error and allergic conjunctivitis in order to reveal possible insights into the pathogenesis in 1015 subjects.MethodsThe patients were divided into four groups: contact lens wearers with allergic conjunctivitis (n= 73), contact lens wearers without allergic conjunctivitis (n= 59), non-contact lens wearers with allergic conjunctivitis (n= 224), and non-contact lens wearers without allergic conjunctivitis (n= 659). The spherical power, cylindrical power, corneal radius, and minimum and maximum corneal refractive powers were measured in all subjects.ResultsIn the non-contact lens wearers, the spherical equivalent and spherical power were significantly lower in patients with allergic conjunctivitis than in patients without allergic conjunctivitis (− 3.01±3.83 D vs− 1.36±3.08 D, P< 0.0001, and− 2.64±3.63 D vs− 1.05±2.88 D, P< 0.0001, respectively), while there was no significant difference in any of the parameters between the contact lens wearers with and without allergic conjunctivitis.Conclusion