VIRUS ANTIBODY SURVEY ON SERA OF RESIDENTS OF THE AMAZON VALLEY IN BRAZIL
VIRUS ANTIBODY SURVEY ON SERA OF RESIDENTS OF THE AMAZON VALLEY IN BRAZIL
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DOI：
10.4269/ajtmh.1958.7.36
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发表时间：
1958-01-01
影响因子：
3.3
通讯作者：
THEILER, M
中科院分区：
文献类型：
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作者：
CAUSEY, OR;THEILER, M
通过小鼠中和试验，对亚马逊流域15个地区居民的血清进行了14种乔木病毒抗体的检测。中和率较高的病毒是黄热病（44.7%）、伊尔赫斯（36.2%）、委内瑞拉马脑炎（VEE）（16.7%）和塞姆利基森林（13.9%）。中和率较低的病毒是登革热I型，9.6%;西尼罗河，6.1%;圣路易斯，5.5%;布尼亚姆韦拉，4.7%;东部马脑炎，4.1%;寨卡，4.0%;乌干达S型，2.1%;登革热II型，2.0%;西部马脑炎，1.6%。Bwamba是唯一一种没有发现抗体的病毒，没有证据表明乌干达S、寨卡、西尼罗河、圣路易斯、登革热II或WEE病毒在亚马逊流域存在。这些试剂获得的阳性结果可能是由于与其他免疫相关试剂的免疫学重叠。
Sera from residents in 15 localities in the Amazon Valley were examined for antibodies to 14 arbor viruses by neutralization tests in mice. Viruses neutralized in high ratios were yellow fever, 44.7%; Ilheus, 36.2%; Venezuelan equine encephalitis (VEE), 16.7%; and Semliki Forest, 13.9%. Viruses neutralized in lower ratios were dengue I, 9.6%; West Nile, 6.1%; St. Louis, 5.5%; Bunyamwera, 4.7%; eastern equine encephalitis (EEE), 4.1%; Zika, 4.0%; Uganda S, 2.1%; dengue II, 2.0%; and western equine encephalitis (WEE), 1.6%. Bwamba was the only virus tested for which no antibodies were found. The evidence is not conclusive that Uganda S, Zika, West Nile, St. Louis, dengue II, or WEE virus occurs in the Amazon Valley. The positive results obtained with these agents may be due to immunological overlap with other immunologically related agents.