A prospective investigation of the relationships among sleep quality, physical symptoms, and depressive symptoms during pregnancy
A prospective investigation of the relationships among sleep quality, physical symptoms, and depressive symptoms during pregnancy
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DOI：
10.1016/j.jad.2009.09.015
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发表时间：
2010-06-01
影响因子：
6.6
通讯作者：
Milgrom, Jeannette
中科院分区：
文献类型：
--
作者：
Kamysheva, Ekaterina;Skouteris, Helen;Milgrom, Jeannette
本研究旨在探讨孕期身体不适与妊娠晚期抑郁症状之间的关系，以及睡眠质量在产前抑郁症状中的中介作用。健康孕妇(N=257)在妊娠早期、中期和晚期分别完成躯体症状问卷、贝克抑郁量表和匹兹堡睡眠问卷。第一个时间点的身体症状和睡眠质量都与妊娠晚期的抑郁症状有中等程度的相关性。与身体症状相关的不适比症状的频率更能预测抑郁症状，尽管结合频率、不适和症状对生活的影响的分数是抑郁症状的最强预测因子。中介模型的分层回归分析结果表明，妊娠早、中期的躯体症状直接预测最后三个月的抑郁症状，并通过睡眠质量差(前瞻性)来中介这种关系。讨论了这些发现对产前护理的临床意义。(C)2009爱思唯尔B.V.保留所有权利。
The aim of this study was to examine the prospective relationship between pregnancy physical discomforts experienced during the second trimester and late pregnancy depressive symptoms, as well as the mediating effect of sleep quality on antenatal depressive symptomatology. Healthy pregnant women (N=257) completed the Physical Symptoms Questionnaire, the Beck Depression Inventory, and the Pittsburgh Sleep Inventory at early-mid second trimester, and then again at late third trimester. Physical symptoms and sleep quality at the first time point were both correlated moderately with depressive symptoms at late pregnancy. Discomfort associated with physical symptoms was a better predictor of depressive symptoms than Frequency of symptoms, although a score combining Frequency, Discomfort and Effect of symptoms on life was the strongest predictor of depressive symptoms. Results of the hierarchical regression analyses of the mediation model indicated that physical symptoms at early-mid second trimester predicted depressive symptoms in the last trimester both directly, and via poor sleep quality (prospectively), which mediated the relationship. The clinical implications of these findings for antenatal care are discussed. (C) 2009 Elsevier B.V. All rights reserved.