Polymer nanoparticles with activated ester surface by using functional surfmers
Polymer nanoparticles with activated ester surface by using functional surfmers
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DOI：
10.1002/macp.200390049
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发表时间：
2003-04
影响因子：
2.5
通讯作者：
M. Herold;H. Brunner;G. Tovar
中科院分区：
文献类型：
--
作者：
M. Herold;H. Brunner;G. Tovar
合成了两种新型可聚合表面活性剂（surfmers）：对[11-（丙烯酰胺基）十一酰氧基]苯基二甲基锍甲基硫酸盐（AUPDS）和对[11-（甲基丙烯酰氨基）十一酰氧基]苯基二甲基锍甲基硫酸盐（MUPDS），并用于制备功能聚合物纳米颗粒。对冲浪者进行了表征（cmc AUPDS = 6.0 ± 0.2 mmol . L -1 ；cmc MUPDS = 3.2 ± 0.2 mmol . L -1 ）并用于以甲基丙烯酸甲酯作为共聚单体的乳液聚合。根据表面活性剂与共聚单体的比例，所得颗粒的动态光散射直径在 109 nm 至 167 nm 之间。扫描电子显微镜证实了非常窄的尺寸分布。通过微电泳测量，颗粒显示出 20 至 24 mV 的 z 电位，这对应于冲浪者带正电的锍基团的静电稳定作用。通过用荧光探针滴定胶乳并随后进行荧光分析来测定颗粒结合的活性酯的反应性。根据乳液聚合中 AUPDS 的起始浓度，每 I g 颗粒固定 6-氨基荧光素 0.8 μmol 至 9.6 μmol
Two new polymerizable surfactants (surfmers), p-[11-(acrylamido)-undecanoyloxy]phenyldimethylsulfonium methylsulfate (AUPDS) and p-[11-(methacrylamido)undecanoyloxy]phenyldimethylsulfonium methylsulfate (MUPDS), were synthesized and used for the preparation of functional polymer nanoparticles. The surfmers were characterized (cmc AUPDS = 6.0 ± 0.2 mmol . L -1 ; cmc MUPDS = 3.2 ± 0.2 mmol . L -1 ) and employed in emulsion polymerization with methyl methacrylate as a comonomer. Depending on the surfmer-to-comonomer ratio, the resulting particles had a dynamic light scattering diameter between 109 nm and 167 nm. Scanning electron microscopy confirmed a very narrow size distribution. The particles showed a ζ-potential of 20 to 24 mV as measured by micro-electrophoresis, corresponding to the electrostatic stabilization by the positively charged sulfonium group of the surfmer. The reactivity of the particle bound active ester was determined by titration of the latex with a fluorescent probe and subsequent fluorescence analysis. 6-Aminofluoresceine was immobilized from 0.8 μmol to 9.6 μmol per I g particles depending on the AUPDS starting concentration in emulsion polymerization