AMPHETAMINE, BARBITURATES, AND ACCOMMODATION-CONVERGENCE.
AMPHETAMINE, BARBITURATES, AND ACCOMMODATION-CONVERGENCE.
复制标题
安非他明、巴比妥类药物和调节趋同。
DOI：
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发表时间：
1963
期刊：
影响因子：
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通讯作者：
G. Westheimer
中科院分区：
文献类型：
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作者：
G. Westheimer
已经证明巴比妥类药物选择性地影响人的眼球运动反应，它们干扰正常的会聚反应1并破坏平滑的跟踪运动。[2]后一种效应与众所周知的巴比妥类药物眼震现象密切相关。3.眼睛对近距离目标的调节似乎不受巴比妥类药物的影响。[1]由于存在一种众所周知的伸展-会聚联带运动，[4]许多人认为这是个体的一种不变特征，因此描述巴比妥酸盐中毒期间联带运动的变化是有意义的。安非他明可能产生相反方向的变化的可能性也被研究，希望能对这些影响起作用的神经水平有一个指示。材料与方法实验对象为几名20岁出头的正常男性学生，无明显的眼内或眼外肌异常，也无过度使用任何药物的病史。
It has been demonstrated that barbiturates selectively influence eye movement responses in man. They interfere with normal convergence responses 1 and abolish the smooth tracking movements. 2 The latter effect is closely associated with the well-known phenomenon of barbiturate nystagmus. 3 Accommodation of the eye for near targets seems unaffected by barbiturates. 1 Since there is a well-known accommodation-convergence synkinesis, 4 thought by many to be an invariable characteristic of an individual, it is of interest to describe the changes in the synkinesis during barbiturate intoxication. The possibility that amphetamine might produce changes in the opposite direction was also investigated in the hope that an indication might be had of the neural level at which these influences operate. Materials and Methods Experimental subjects were several normal male students in their early twenties, with no demonstrable intra- or extraocular muscle abnormality, and with no history involving excessive use of any pharmacologic