Prevalence of Dementia in Elderly Living in Two Cities of Central Africa: The EDAC Survey

Prevalence of Dementia in Elderly Living in Two Cities of Central Africa: The EDAC Survey
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DOI:
10.1159/000320247
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发表时间:
2010-01-01
影响因子:
2.4
通讯作者:
Preux, Pierre-Marie
Preux, Pierre-Marie
中科院分区:
医学4区
文献类型:
--
作者:
Guerchet, Maelenn;M'belesso, Pascal;Preux, Pierre-Marie

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背景:低收入和中等收入国家的痴呆症数据仍然需要量化这种疾病的负担。这项多中心横断面研究旨在估计中非两个大城市痴呆症的患病率。研究方法:在班吉(中非共和国)和布拉柴维尔(刚果)地区,对6 - 65岁的老年人进行了一般人口挨家挨户的调查。受试者进行了筛选与社区筛选访谈痴呆症和五个字的测试。根据DSM-IV标准和NINCDS-ADRDA提出的阿尔茨海默病的临床标准进行痴呆的诊断。结果:我们在班吉招募了496名受试者,在布拉柴维尔招募了520名受试者。班吉和布拉柴维尔的痴呆患病率估计分别为8.1%(95% CI = 5.8-10.8)和6.7%(95% CI = 4.7-9.2)。结论:中非城市地区痴呆症的患病率接近高收入国家。版权所有(C)2010 S. Karger AG,巴塞尔
Background: Data on dementia from low-and middle-income countries are still necessary to quantify the burden of this condition. This multicenter cross-sectional study aimed at estimating the prevalence of dementia in 2 large cities of Central Africa. Methods: General population door-to-door surveys were conducted in the districts of Bangui (Republic of Central Africa) and Brazzaville (Congo) in elderly aged 6 65 years. The subjects were screened with the Community Screening Interview for Dementia and the Five-Words Test. Diagnosis of dementia was made according to the DSM-IV criteria and to the clinical criteria proposed by the NINCDS-ADRDA for Alzheimer's disease. Results: We enrolled 496 subjects in Bangui and 520 in Brazzaville. The prevalence of dementia was estimated at 8.1% (95% CI = 5.8-10.8) in Bangui and 6.7% (95% CI = 4.7-9.2) in Brazzaville. Conclusion: The prevalence of dementia in urban areas of Central Africa is close to those observed in high-income countries. Copyright (C) 2010 S. Karger AG, Basel