NADPH-diaphorase histochemistry reveals cone distributions in adult human retinae.
NADPH-diaphorase histochemistry reveals cone distributions in adult human retinae.
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NADPH-心肌黄酶组织化学揭示了成人视网膜中的视锥细胞分布。
DOI：
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发表时间：
1993
期刊：
影响因子：
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通讯作者：
F. Billson
中科院分区：
文献类型：
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作者：
C. Diaz‐Araya;J. Provis;F. Billson
应用NADPH黄递酶组织化学方法对44 ~ 68岁成人视网膜视锥细胞进行了形态学分析。视网膜的NADPH-黄递酶的反应性，存在于血管壁，无长突细胞和锥和杆外段;一个亚群的反应性较低的配置文件，形态上类似于锥，可能代表蓝色锥人口。规则间隔的视锥细胞对（一个强标记的视锥细胞和一个弱标记的视锥细胞）在整个视网膜中也很明显，并且最常见于沿着水平子午线，特别是朝向周边。使用图像分析评估标记的锥体外节的直径和分布。成年人视网膜的视锥密度范围从颞叶周边的每平方毫米2000个到中央凹的每平方毫米82，000到120，000个。分布模式证实了存在一个锥条纹，从中央凹区域延伸到鼻视网膜，但没有证据的上下不对称检测。
NADPH-diaphorase histochemistry was used to identify and analyse the topography of cones in adult human retinae (in the age range 44 to 68 years). Retinae were treated for NADPH-diaphorase reactivity, present in vascular walls, amacrine cells and cone and rod outer segments; a subpopulation of less intensely reactive profiles, morphologically resembling cones, possibly represents the blue cone population. Regularly spaced pairs of cones (one intensely labelled and one weakly labelled cone) were also apparent throughout the retina, and were most common along the horizontal meridian, particularly towards the periphery. The diameters and distributions of labelled cone outer segments were assessed using image analysis. Cone density in the adult retina ranged from 2000 per mm2 in the temporal periphery, to 82,000 to 120,000 per mm2 at the fovea centralis. Distribution patterns confirmed the presence of a cone streak, extending from the foveal region into nasal retina, but no evidence of superior-inferior asymmetry was detected.