Spectrum of Cardiovascular Diseases in Asian-American Racial/Ethnic Subgroups
Spectrum of Cardiovascular Diseases in Asian-American Racial/Ethnic Subgroups
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DOI：
10.1016/j.annepidem.2011.04.004
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发表时间：
2011-08-01
影响因子：
5.6
通讯作者：
Palaniappan, Latha P.
中科院分区：
文献类型：
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作者：
Holland, Ariel T.;Wong, Eric C.;Palaniappan, Latha P.
目得：比较亚裔美国人亚组中冠心病（CHD）、卒中和外周血管疾病（PVD）的患病率（亚洲印度人、中国人、菲律宾人、日本人、韩国人和越南人）和非西班牙裔白色（NHW）受试者在加州的一个混合支付者门诊医疗保健组织中。2007年至2010年，我们检查了94，423名亚洲和NHW患者的电子健康记录。CHD、中风和PVD的经校正的患病率（由医生国际疾病分类第9版代码定义）直接标准化为NHW人群。使用logistic回归分析计算每个亚洲亚组，按性别，与NHWs.RESULTS：年龄调整的患病率的范围是：冠心病（1.7%-5.2%），中风（0.3%-1.8%），PVD（0.9%-3.4%）。菲律宾女性冠心病的调整优势比明显高于（1.66; 95%置信区间; 1.13-2.43）和男子（1.47，1.05-2.06）和亚洲印度男性（1.77，1.43-2.21），中国女性（0.72，0.55-0.94）和男性（0.78，0.65-0.93）显著低于非健康工作者。菲律宾女性中风的几率明显更大（2.02，1.22-3.34）。所有亚洲亚组的PVD几率通常较低。结论：亚洲亚组之间CHD、中风和PVD的患病率存在相当大的异质性。未来的研究应该对亚洲亚组和心血管结局进行分类，以告知有针对性的预防和治疗工作。Ann Epidemiol 2011;21：608-614. (C)2011 Elsevier Inc. All rights reserved.
PURPOSE: To compare the prevalence of coronary heart disease (CHD), stroke, and peripheral vascular disease (PVD) across Asian-American subgroups (Asian Indian, Chinese, Filipino, Japanese, Korean, and Vietnamese) and non-Hispanic white (NHW) subjects in a mixed-payer, outpatient health care organization in California.METHODS: Electronic health records from 2007 to 2010 were examined for 94,423 Asian and NHW patients. Age-adjusted prevalence rates of CHD, stroke, and PVD, defined by physician International Classification of Diseases, Version 9, codes, were directly standardized to the NHW population. Age-adjusted odds ratios were calculated by the use of logistic regression for each Asian subgroup, by sex, compared with NHWs.RESULTS: The range of age-adjusted prevalence rates were: CHD (1.7%-5.2%), stroke (0.3%-1.8%), and PVD (0.9%-3.4%). The adjusted odds ratios of CHD were significantly higher for Filipino women (1.66; 95% confidence interval; 1.13-2.43) and men (1.47, 1.05-2.06) and Asian Indian men (1.77, 1.43-2.21), and significantly lower for Chinese women (0.72, 0.55-0.94) and men (0.78, 0.65-0.93), compared with NHWs. The odds of stroke were significantly greater for Filipino women (2.02, 1.22-3.34). The odds of PVD were generally lower for all Asian subgroups.CONCLUSION: There is considerable heterogeneity across Asian subgroups for prevalent CHD, stroke, and PVD. Future research should disaggregate Asian subgroups and cardiovascular outcomes to inform targeted prevention and treatment efforts. Ann Epidemiol 2011;21:608-614. (C) 2011 Elsevier Inc. All rights reserved.