Blood and Marrow Transplant Clinical Trials Network Study 1102 heralds a new era in hematopoietic cell transplantation in high-risk myelodysplastic syndromes: Challenges and opportunities in implementation.

Blood and Marrow Transplant Clinical Trials Network Study 1102 heralds a new era in hematopoietic cell transplantation in high-risk myelodysplastic syndromes: Challenges and opportunities in implementation.
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DOI:
10.1002/cncr.33826
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发表时间:
2021-12-01
期刊:
影响因子:
6.2
通讯作者:
Khera N
Khera N
中科院分区:
医学1区
文献类型:
--
作者:
Warlick ED;Ustun C;Andreescu A;Bonagura AF;Brunner A;Chandra AB;Foran JM;Juckett MB;Kindwall-Keller TL;Klimek VM;Pease DF;Steensma DP;Waldman BM;Horowitz MM;Burns LJ;Khera N

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患有晚期骨髓增生异常综合征(MDS)的人如果接受骨髓移植(BMT)而不是其他疗法,可能会活得更长。然而,只有15%的MDS患者实际上得到了BMT。传播有关BMT挽救生命的进展的消息;确保每个人都能负担得起医疗保健;为患者和家庭提供情感支持;帮助患者和家庭获得交通和住房,如果他们需要旅行进行移植;改善对代表性不足的种族和民族背景的人的护理。专家说,社区医生和移植医生应该与保险公司和患者倡导团体合作:与非移植疗法相比,BMT CTN 1102证明了接受异基因造血细胞移植的高危骨髓增生异常综合征患者的上级生存率。本文描述了一个框架,以扩大获得移植的高危骨髓增生异常综合征患者,以确保最佳实施本研究的结果。
People who have advanced myelodysplastic syndromes (MDS) may live longer if they get a bone marrow transplant (BMT) instead of other therapies. However, only 15% of people with MDS actually get BMT. spread this news about life-saving advances in BMT; ensure that everyone can afford health care; provide emotional support for patients and families; help patients and families get transportation and housing if they need to travel for transplant; improve care for people of under-represented racial and ethnic backgrounds. Experts say community doctors and transplant doctors should team up with insurance companies and patient advocacy groups to: BMT CTN 1102 demonstrated superior survival for patients with high risk myelodysplastic syndromes undergoing allogeneic hematopoietic cell transplantation compared to non-transplant therapies. The article describes a framework to expand access to transplantation for patients with high risk myelodysplastic syndromes to ensure optimal implementation of the results of this study.
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