Racial differences in visceral adipose tissue but not anthropometric markers of health-related variables
Racial differences in visceral adipose tissue but not anthropometric markers of health-related variables
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DOI：
10.1152/jappl.2000.89.2.636
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发表时间：
2000-08-01
影响因子：
3.3
通讯作者：
Feldman, BB
中科院分区：
文献类型：
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作者：
Perry, AC;Applegate, EB;Feldman, BB
本研究旨在确定内脏脂肪组织（VAT）和/或其人体测量替代物是否可以显着预测超重白人（CC）（n = 36）和非洲裔美国人（AA）（n = 30）妇女的健康相关变量（HRV）。通过磁共振成像，结果显示CC组VAT体积和面积均显著高于AA组（P < 0.0001），三酰甘油水平也显著高于AA组（P = 0.009）。此外，VAT体积、种族和VAT体积×种族相互作用可显著预测三酰甘油（P = 0.0094）、高密度脂蛋白胆固醇（P = 0.0057）、胰岛素（P = 0.0002）和胰岛素抵抗（P < 0.0001）。此外，胰岛素（P = 0.040）和胰岛素抵抗（P = 0.003）的VAT体积x种族相互作用具有显著性。在一项单独的分析中，腰围和种族预测了相同的变量。我们的研究结果支持使用的体积或面积的增值税在预测心率变异性CC妇女，但是，它的使用AA妇女似乎有限。相比之下，腰围可以为CC和AA女性提供合适的VAT替代方案;然而，VAT显然代表了更强大的预测因素。
This study sought to determine whether visceral adipose tissue (VAT) and/or its anthropometric surrogates could significantly predict health-related variables (HRV) in overweight Caucasian (CC) (n = 36) and African-American (AA) (n = 30) women. With the use of magnetic resonance imaging, findings showed significantly higher volume and area of VAT (P < 0.0001 for both) as well as higher triacylglycerol (P = 0.009) in CC compared with AA women. Furthermore, VAT volume, race, and VAT volume x race interaction could significantly predict triacylglycerol (P = 0.0094), high-density lipoprotein cholesterol (P = 0.0057), insulin (P = 0.0002), and insulin resistance (P < 0.0001). Additionally, the VAT volume x race interaction for insulin (P = 0.040) and insulin resistance (P = 0.003) was significant. In a separate analysis, waist circumference and race predicted the identical variables. Our results support the use of volume or area of VAT in predicting HRV in CC women; however, its use in AA women appears limited. In contrast, waist circumference can provide a suitable VAT alternative for both CC and AA women; however, VAT clearly represents the more powerful predictor.