Biotin and glucose metabolism.

Biotin and glucose metabolism.
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生物素和葡萄糖代谢。

DOI:
10.1139/o70-079
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发表时间:
1970
期刊:
Canadian journal of biochemistry
影响因子:
--
通讯作者:
H. C. Hong
H. C. Hong
中科院分区:
--
文献类型:
--
作者:
K. Dakshinamurti;L. Tarrago;H. C. Hong

文献摘要

被引文献

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生物素增强糖尿病大鼠肝脏葡萄糖激酶活性。使用蛋白质和RNA合成抑制剂的实验表明,这是通过从头蛋白质合成介导的。生物素处理也增加了其他关键糖酵解激酶,磷酸果糖激酶和丙酮酸激酶的活性,但对磷酸己糖异构酶等双功能酶没有影响。
Biotin enhances liver glucokinase in the diabetic rat. Experiments using inhibitors of protein and RNA synthesis suggest that this is mediated through de novo protein synthesis. Biotin treatment also increases the activities of other key glycolytic kinases, phosphofructokinase and pyruvate kinase, but has no effect on a bifunctional enzyme like phosphohexose isomerase.