Weighing Evidence "Steampunk" Style via the Meta-Analyser.

Weighing Evidence "Steampunk" Style via the Meta-Analyser.
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DOI:
10.1080/00031305.2016.1165735
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发表时间:
2016-10-01
期刊:
The American statistician
影响因子:
--
通讯作者:
Jackson C
Jackson C
中科院分区:
其他
文献类型:
--
作者:
Bowden J;Jackson C

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漏斗图是荟萃分析汇总数据估计值的图形可视化,是检测偏离标准建模假设的有用工具。虽然可能没有得到广泛的认可,但漏斗图的简单扩展可以帮助在更基本的层面上直观地解释元分析背后的数学,将其等同于确定物理系统的质心。在剑桥科学节上,我们用这个类比向年轻观众解释了权衡证据和有偏见证据的概念,没有借助精确的定义或统计公式,只得到了福尔摩斯的一点帮助!继科学博览会之后,我们开发了一个交互式网络应用程序(名为Meta-Analyser),将这些想法带给更广泛的受众。我们设想,我们的应用程序将是一个有用的工具,为研究人员解释他们的数据。首先,为了便于简单理解固定和随机效应建模方法;第二,评估离群值的重要性;第三,显示调整小研究偏倚的影响。这最终的目的是通过引入一个新的图形解释著名的Egger回归方法来实现的。
The funnel plot is a graphical visualization of summary data estimates from a meta-analysis, and is a useful tool for detecting departures from the standard modeling assumptions. Although perhaps not widely appreciated, a simple extension of the funnel plot can help to facilitate an intuitive interpretation of the mathematics underlying a meta-analysis at a more fundamental level, by equating it to determining the center of mass of a physical system. We used this analogy to explain the concepts of weighing evidence and of biased evidence to a young audience at the Cambridge Science Festival, without recourse to precise definitions or statistical formulas and with a little help from Sherlock Holmes! Following on from the science fair, we have developed an interactive web-application (named the Meta-Analyser) to bring these ideas to a wider audience. We envisage that our application will be a useful tool for researchers when interpreting their data. First, to facilitate a simple understanding of fixed and random effects modeling approaches; second, to assess the importance of outliers; and third, to show the impact of adjusting for small study bias. This final aim is realized by introducing a novel graphical interpretation of the well-known method of Egger regression.
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