Plasma Adrenaline Increases in Anesthetized Patients Given Electro-acupuncture Before Surgery
Plasma Adrenaline Increases in Anesthetized Patients Given Electro-acupuncture Before Surgery
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DOI：
10.1111/j.1526-4637.2010.00878.x
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发表时间：
2010-01-01
期刊：
影响因子：
3.1
通讯作者：
Akeson, Jonas
中科院分区：
文献类型：
--
作者：
Kvorning, Nina;Akeson, Jonas
目的：在麻醉病人中，电针（EA）被发现可以减轻七氟醚对手术引起的颅和脊髓运动反应的抑制，而不影响麻醉水平。潜在的机制尚不清楚。在本研究中，分析血液样本以评估在七氟烷麻醉下接受EA的患者对手术的临床运动反应增加是否也反映在较高的血浆儿茶酚胺、促肾上腺皮质激素（ACTH）或cortisol.Methods水平上。45名健康女性患者在1.8%七氟烷稳态麻醉下手术30分钟后，计划通过腹腔镜进行绝育，随机接受双侧2 Hz脉冲群EA（研究组; n = 22）或对照组（对照组; n = 23）结果：在给予EA刺激的患者中，手术30分钟后发现肾上腺素的血浆水平接近较高的麻醉前水平，在对照组中保持较低水平（P < 0.05）-与EA组对皮肤切口的较强临床运动反应一致。血浆去甲肾上腺素，促肾上腺皮质激素和皮质醇水平没有改变或different between the two groups.Conclusion.在七氟烷麻醉下给予针刺的患者的颅和脊髓运动反应的手术的临床促进与肾上腺素的血浆水平增加，可能反映交感神经激活。
Purpose.In anesthetized patients, electro-acupuncture (EA) has been found to reduce sevoflurane-induced suppression of cranial and spinal motor responses to surgery without influencing the level of anesthesia. The underlying mechanisms are unclear. In the present study, blood samples were analyzed to evaluate if the increased clinical motor responses to surgery in patients subjected to EA under sevoflurane anesthesia are also reflected in higher plasma levels of catecholamines, adrenocorticotrophic hormone (ACTH), or cortisol.Methods.Blood samples were obtained before anesthetic induction, soon after the study or control procedures had been completed under general anesthesia, and after 30 minutes of surgery under steady-state anesthesia with 1.8% of sevoflurane, in 45 healthy female patients, scheduled for sterilization by laparoscopy, randomized for bilateral 2 Hz-burst EA (study group; n = 22) or control (control group; n = 23) procedures.Result.Plasma levels of adrenaline were found to approach the higher preanesthetic level after 30 minutes of surgery in patients given EA stimulation but to remain low in control patients (P < 0.05)-in agreement with the stronger clinical motor responses to skin incision in the EA group. Plasma levels of noradrenaline, ACTH, and cortisol did not change in or differ between the two groups.Conclusion.The clinical facilitation of both cranial and spinal motor responses to surgery in patients given acupuncture under sevoflurane anesthesia is associated with increased plasma levels of adrenaline, possibly reflecting sympathetic activation.