Objectively Measured Sedentary Behavior, Physical Activity, and Plasma Lipids in Overweight and Obese Children
Objectively Measured Sedentary Behavior, Physical Activity, and Plasma Lipids in Overweight and Obese Children
复制标题
DOI：
10.1002/oby.20005
复制
发表时间：
2013-02-01
期刊：
影响因子：
6.9
通讯作者：
Baur, Louise A.
中科院分区：
文献类型：
--
作者：
Cliff, Dylan P.;Okely, Anthony D.;Baur, Louise A.
目的：本研究探讨了超重和肥胖儿童客观测量的久坐行为、轻体力活动（LPA）和中高强度体力活动（MVPA）与血脂之间的关系。设计与方法：对126名5.5 ~ 9.9岁儿童进行横断面分析。使用加速度计评估久坐行为、LPA和MVPA。分析空腹血样中的血浆脂质（高密度脂蛋白胆固醇[HDL-C]、低密度脂蛋白胆固醇[LDL-C]、总胆固醇[TC]和甘油三酯[TG]）。结果：MVPA与血脂无相关性（P < 0.05）。与年龄、性别、能量摄入和腰围z-score无关，久坐行为和LPA与HDL-C相关（β = -0.23, 95% CI -0.42至-0.04,P = 0.020; β = 0.20, 95% CI 0.14至0.39,P = 0.036）。在额外调整了MVPA（久坐行为：β = -0.22, 95% CI -0.44至0.006,P = 0.056; LPA: β = 0.19, 95% CI -0.005至0.38,P = 0.056）后，这种关联的强度仍然存在。结论：用至少低脂运动取代久坐时间可能有助于超重和肥胖儿童健康HDL-C水平的发展，而与肥胖无关。改善超重和肥胖儿童血浆HDL-C的综合预防和治疗策略，除了促进健康的肥胖水平、健康的饮食行为和MVPA外，还应以减少总久坐时间和促进LPA的益处为目标。
Objective: This study examines the associations between objectively measured sedentary behavior, light physical activity (LPA), and moderate-to-vigorous physical activity (MVPA), and plasma lipids in overweight and obese children.Design and Methods: Cross-sectional analyses were conducted among 126 children aged 5.5-9.9 years. Sedentary behavior, LPA, and MVPA were assessed using accelerometry. Fasting blood samples were analyzed for plasma lipids (high-density lipoprotein cholesterol [HDL-C], low-density lipoprotein cholesterol [LDL-C], total cholesterol [TC], and triglycerides [TG]).Results: MVPA was not related to plasma lipids (P > 0.05). Independent of age, sex, energy intake, and waist circumference z-score, sedentary behavior and LPA were associated with HDL-C (beta = -0.23, 95% CI -0.42 to -0.04, P = 0.020; beta = 0.20, 95% CI 0.14 to 0.39, P = 0.036, respectively). The strength of the associations remained after additionally adjusting for MVPA (sedentary behavior: beta = -0.22, 95% CI -0.44 to 0.006, P = 0.056; LPA: beta = 0.19, 95% CI -0.005 to 0.38, P = 0.056, respectively).Conclusion: Substituting at least LPA for sedentary time may contribute to the development of healthy HDL-C levels among overweight and obese children, independent of their adiposity. Comprehensive prevention and treatment strategies to improve plasma HDL-C among overweight and obese children should target reductions in total sedentary time and promote the benefits of LPA, in addition to promoting healthy levels of adiposity, healthy dietary behaviors, and MVPA.