A convenient procedure for the synthesis of nonsymmetrical bivalent selective serotonin reuptake inhibitors using polymer-supported reagents.

A convenient procedure for the synthesis of nonsymmetrical bivalent selective serotonin reuptake inhibitors using polymer-supported reagents.
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使用聚合物支持的试剂合成非对称二价选择性血清素再摄取抑制剂的便捷程序。

DOI:
10.1016/s0960-894x(00)00576-x
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发表时间:
2000
影响因子:
2.7
通讯作者:
Kozikowski,AP
Kozikowski,AP
中科院分区:
医学4区
文献类型:
--
作者:
Tamiz,AP;Conti,P;Zhang,M;Johnson,KM;Kozikowski,AP

文献摘要

被引文献

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A convenient synthesis of nonsymmetrical bivalent inhibitors of the serotonin transporter is described. The synthesis utilizes polymer-supported reagents that allow for rapid access to novel bivalent ligands without the need for isolation or purification of synthetic intermediates.