A stereologic analysis of collagen phagocytosis by fibroblasts in three soft connective tissues with differing rates of collagen turnover
A stereologic analysis of collagen phagocytosis by fibroblasts in three soft connective tissues with differing rates of collagen turnover
复制标题
具有不同胶原周转率的三种软结缔组织中成纤维细胞对胶原蛋白吞噬作用的立体学分析
DOI：
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发表时间：
1981
期刊：
影响因子：
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通讯作者：
D. Deporter
中科院分区：
文献类型：
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作者：
E. Svoboda;A. Shiga;D. Deporter
本研究的目的是评估胶原蛋白吸收的吞噬机制在软结缔组织正常更新和重塑中的重要性。使用电子显微镜体视学方法对大鼠皮肤、附着牙龈和牙周膜中成纤维细胞的胶原吞噬作用进行定量。牙周膜所含的吞噬胶原蛋白分别是附着牙龈和皮肤的 5 倍和 15 倍。此外，对于检查的每个组织，观察到被吞噬的胶原蛋白的量与已知的成熟胶原蛋白周转率之间呈正相关。
The purpose of this study was to assess the importance of the phagocytic mechanism of collagen resorption in the normal turnover and remodelling of soft connective tissues. Collagen phagocytosis by fibroblasts in rat skin, attached gingiva, and periodontal ligament was quantitated using the methodology of electron microscopic stereology. Periodontal ligament contained five and 15 times as much phagocytosed collagen as attached gingiva and skin respectively. Also, for each tissue examined, a positive correlation was observed between the amount of collagen phagocytosed and the known rate of mature collagen turnover.