Another method that shows organization in persistent AF? That's a RAAP.
Another method that shows organization in persistent AF? That's a RAAP.
复制标题
另一种显示持久 AF 组织的方法？
DOI：
10.1111/jce.14215
复制
发表时间：
2019
影响因子：
2.7
通讯作者：
Zaman,JunaidAB
中科院分区：
文献类型：
--
作者：
Baykaner,Tina;Zaman,JunaidAB
肺静脉隔离术(PVI)消融房颤是治疗症状性房颤、提高生活质量和延长生存期的基石。然而，在阵发性和持续性房颤患者中，PVI的远期成功率仍在40-70%(3)。更好地了解房颤的传导机制，而不是针对引发房颤的触发因素；应该有助于改善房颤患者的消融结果的最终目标。房颤的时空组织或重复模式已在人类中得到证实，方法结合了主频率(4)、Shannon熵(5)、ECGi(6)、焦点脉冲和转子映射(FIRM)(7)和电流图(8)，证明了在房颤传导过程中存在层次性和稳定性。这激励了当前的工业和研究努力，将这些区域确定为治疗的辅助目标。
Atrial fibrillation (AF) ablation by pulmonary vein isolation (PVI) is the cornerstone of therapy for symptomatic AF, improving quality of life and prolonging survival in several populations (1, 2). Nevertheless, the long term success of PVI is still in the range of 40–70% in patients with paroxysmal and persistent AF (3). A better understanding of mechanisms of fibrillatory conduction, beyond targeting the triggers initiating AF; should contribute to the ultimate goal to improve ablation outcomes for AF patients.Spatiotemporal organization or repetitive patterns in AF have been demonstrated in humans using methods incorporating phase analysis such as dominant frequency (4), Shannon entropy (5), ECGi (6), Focal Impulse and Rotor Mapping (FIRM)(7), and electrographic flow mapping (8), proving the presence of both hierarchy and stability during fibrillatory conduction. This motivates current industry and research efforts to identify these areas as adjunctive targets for therapy.