Acute heat stress induces oxidative stress in broiler chickens
Acute heat stress induces oxidative stress in broiler chickens
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DOI：
10.1016/j.cbpa.2006.01.032
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发表时间：
2006-05-01
影响因子：
2.3
通讯作者：
Buyse, Johan
中科院分区：
文献类型：
--
作者：
Lin, Hai;Decuypere, Eddy;Buyse, Johan
研究了高温对肉鸡血浆、肝脏和心脏组织的应激反应和可能的氧化损伤。将80只5周龄肉仔鸡暴露于32 ℃下6h。测定血浆、肝脏和心脏组织脂质过氧化程度、超氧化物歧化酶活性和总抗氧化能力。同时测定热暴露前、热暴露后3 h和6 h血液中葡萄糖、尿酸盐、三碘甲状腺原氨酸、甲状腺素、皮质酮、血浆铜蓝蛋白和肌酸激酶等代谢产物的含量。结果表明，急性热暴露（32 ℃，6h）可诱导5周龄肉仔鸡产生氧化应激。结果表明，升高的体温可以诱导参与诱导氧化应激的代谢变化。肉鸡急性热暴露时肝脏比心脏更易受到氧化应激的影响。氧化应激是肉鸡热应激反应的一部分。(c)2006年爱思唯尔公司All rights reserved.
The stress responses and possible oxidative damage in plasma, liver and heart were investigated in broiler chickens acutely exposed to high temperature. Eighty 5-week old broiler chickens were exposed to 32 degrees C for 6h. The extent of lipid peroxidation, activities of superoxide dismutase and total antioxidant power in plasma, liver and heart tissues were investigated. Meanwhile, the blood metabolites such as glucose, urate, triiodothyronine, thyroxine, corticosterone, ceruloplasmin and creatine kinase were measured before and after 3 and 6h of heat exposure. The results showed that oxidative stress could be induced in 5-week old broiler chickens by acute heat exposure (32 degrees C, 6h). The results suggest that the elevated body temperature can induce the metabolic changes that are involved in the induction of oxidative stress. The liver is more susceptible to oxidative stress than heart during acute heat exposure in broiler chickens. The oxidative stress should be considered as part of the stress response of broiler chickens to heat exposure. (c) 2006 Elsevier Inc. All rights reserved.