Brain regions essential for word comprehension: Drawing inferences from patients.
Brain regions essential for word comprehension: Drawing inferences from patients.
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DOI：
10.1002/ana.24941
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发表时间：
2017-06
影响因子：
11.2
通讯作者：
Fridriksson J
中科院分区：
文献类型：
--
作者：
Hillis AE;Rorden C;Fridriksson J
损伤缺陷关联研究很重要，因为它们可以揭示特定功能所必需的大脑区域，但有时似乎会产生相互矛盾的结果。我们的目的是展示如何避免病变研究的陷阱，并从后颞上回在听觉单词理解中的作用的研究中获得收敛的结果。我们回顾了已发表的关于听觉理解损伤的研究，并提出了急性和慢性中风的新数据，以弥补一些先前研究的不足。结果表明，来自不同病变研究的积极结果如何趋同，为特定区域在给定行为中的作用提供了强有力的证据。
Lesion-deficit association studies are important as they can reveal brain regions essential for specific functions, but sometimes appear to yield conflicting results. We aimed to show how pitfalls of lesions studies can be avoided, and converging results obtained, illustrating from studies of the role of posterior superior temporal gyrus in auditory word comprehension. We review published lesion studies on auditory comprehension and present new data from both acute and chronic stroke that address weaknesses in some previous studies. Results demonstrate how convergence of positive results from diverse lesion studies provides strong evidence for the role of a particular region in a given behavior.