Evaluation Of Subjective Cognitive Function Using The Cognitive Complaints In Bipolar Disorder Rating Assessment (COBRA) In Japanese Adults
Evaluation Of Subjective Cognitive Function Using The Cognitive Complaints In Bipolar Disorder Rating Assessment (COBRA) In Japanese Adults
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DOI：
10.2147/ndt.s218382
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发表时间：
2019-01-01
影响因子：
3.2
通讯作者：
Kusumi, Ichiro
中科院分区：
文献类型：
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作者：
Toyoshima, Kuniyoshi;Inoue, Takeshi;Kusumi, Ichiro
目的：研究抑郁症状，主观认知功能，生活质量在日本成年人使用的认知投诉双相情感障碍评定量表（COBRA）。患者和方法：我们评估了585名成年社区志愿者使用患者健康问卷-9（PHQ-9）的抑郁症状和主观认知功能的评价的COBRA。此外，我们还使用了8个项目的简式健康调查表和希恩残疾量表，以评估生活质量（QoL.Results）的主观认知功能的措施与抑郁症状和QoL显着相关。结构方程模型表明，抑郁症状直接和间接降低生活质量，通过其对主观认知功能障碍的影响。抑郁症状的措施更密切相关的生活质量比主观认知functions.Limitations的措施：研究参与者是一般成年人社区志愿者，包括健康的人，因此，这些结果可能无法推广到抑郁症或双相情感障碍患者。此外，本研究的横截面设计防止识别参数之间的因果关系。结论：主观认知功能的变化可能会影响生活质量通过抑郁症状。主观认知功能的评估可能有助于识别降低生活质量的因素。
Purpose: To examine the relationship between depressive symptoms, subjective cognitive function, and quality of life in Japanese adults using the Cognitive Complaints in Bipolar Disorder Rating Assessment (COBRA).Patients and methods: We evaluated 585 adult community volunteers using the Patient Health Questionnaire-9 (PHQ-9) for evaluation of depressive symptoms and the COBRA for evaluation of subjective cognitive function. We additionally used the 8-item Short-Form Health Survey and the Sheehan Disability Scale to evaluate the quality of life (QoL).Results: Measures of subjective cognitive function were significantly correlated with depressive symptoms and QoL. Structural equation modeling demonstrated that depressive symptoms directly and indirectly decreased QoL via their effects on subjective cognitive dysfunction. Measures of depressive symptoms were more closely related to QoL than were measures of subjective cognitive function.Limitations: Study participants were general adult population community volunteers and included healthy people; thus, these results may not be generalizable to patients with depression or bipolar disorder. In addition, the cross-sectional design of this study prevented the identification of causal relationships among the parameters.Conclusion: Changes in subjective cognitive function may affect QoL via depressive symptoms. Evaluations of subjective cognitive function may help identify factors that reduce QoL.