Intensive intervention for alcohol-dependent smokers in early recovery: A randomized trial
Intensive intervention for alcohol-dependent smokers in early recovery: A randomized trial
复制标题
DOI：
10.1016/j.drugalcdep.2011.09.026
复制
发表时间：
2012-05-01
影响因子：
4.2
通讯作者：
Hall, Sharon M.
中科院分区：
文献类型：
--
作者：
Carmody, Timothy P.;Delucchi, Kevin;Hall, Sharon M.
简介：本研究的目的是探讨酒精依赖的吸烟者在早期recovery.Methods：共162酒精依赖的吸烟者的强化戒烟干预的有效性被随机分为两组，一组是强化戒烟干预，另一组是常规护理。强化干预包括16个疗程的个体认知行为疗法（CBT）和持续26周的尼古丁替代疗法。家庭护理包括转诊到一个独立的戒烟计划，提供不同持续时间的戒烟咨询和指南一致的药物。主要的戒烟结果是验证7天的点患病率禁欲（PPA）在12，26，38，和52 weeks.Results：在12和26周，验证7天的点患病率戒烟率是显着高于强化干预组比常规护理组（均P = 0.03）。然而，两个治疗组的戒烟率在38周或52周时没有显著差异。验证30天的酒精戒断率没有显着不同的两个治疗组在任何后续assessment.Conclusions：密集的戒烟干预产生了更高的短期戒烟率，而不会危及清醒。长期护理模式可能有助于在酒精治疗的第一年甚至更长时间内维持戒烟。希望这样的研究将为制定更有效的酒精和烟草使用障碍的干预措施提供信息。出版社：Elsevier爱尔兰Ltd.
Introduction: The purpose of this study was to investigate the efficacy of an intensive tobacco cessation intervention for alcohol-dependent smokers in early recovery.Methods: A total of 162 alcohol-dependent smokers were randomized to either intensive intervention for smoking cessation or usual care. The intensive intervention consisted of 16 sessions of individual cognitive behavior therapy (CBT) and combination nicotine replacement therapy that lasted 26 weeks. Usual care involved referral to a free-standing smoking cessation program that provided smoking cessation counseling of varying duration and guideline-concordant medications. The primary cessation outcome was verified 7-day point prevalence abstinence (PPA) at 12, 26, 38, and 52 weeks.Results: At 12 and 26 weeks, the verified 7-day point-prevalence quit rate was significantly higher for the intensive intervention group than for the usual care group (both p = 0.03). However, the quit rates for the two treatment groups were not significantly different at 38 or 52 weeks. Verified 30-day alcohol abstinence rates were not significantly different for the two treatment groups at any of the follow-up assessments.Conclusions: The intensive smoking cessation intervention yielded a higher short-term smoking quit rate without jeopardizing sobriety. A chronic care model might facilitate maintenance of smoking cessation during the first year of alcohol treatment and perhaps for longer periods of time. It is hoped that studies such as this will inform the development of more effective interventions for concurrent alcohol and tobacco use disorders. Published by Elsevier Ireland Ltd.