ORAL-CONTRACEPTIVES AND BREAST-CANCER
ORAL-CONTRACEPTIVES AND BREAST-CANCER
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DOI：
10.1093/oxfordjournals.aje.a113030
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发表时间：
1980-01-01
影响因子：
5
通讯作者：
ROTHMAN, KJ
中科院分区：
文献类型：
--
作者：
JICK, H;WALKER, AM;ROTHMAN, KJ
使用和不使用口服避孕药 (OC) 的乳腺癌发病率是由美国华盛顿州西雅图普吉特湾的团体健康合作社确定的，该合作社是一个医疗保健组织，负责维护诊断和门诊用药的计算机文件。在 45 岁或以下的女性中，使用者和非使用者的发病率几乎相同。在 45 岁以上的绝经前女性中，当前使用 OC 与乳腺癌之间存在正相关，46-50 岁女性的风险比估计值和 90% 置信区间为 4.0 (1.8-9.0)，51-55 岁女性为 15.5 (5.2-46)。
The incidence of breast cancer among users and non-users of oral contraceptives (OC) was determined at the Group Health Cooperative of Puget Sound, Seattle, Washington [USA], a health care organization which maintains computer files of diagnoses and outpatient drug use. In women 45 yr of age or younger, the incidence was nearly identical in users and non-users. In premenopausal women over 45 yr of age, there was a positive association between current OC use and breast cancer, the risk ratio estimates and 90% confidence intervals being 4.0 (1.8-9.0) in women 46-50 yr of age and 15.5 (5.2-46) in women 51-55 yr of age.