Aerobic capacity in adults with various congenital heart diseases
Aerobic capacity in adults with various congenital heart diseases
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DOI：
10.1016/s0002-9149(00)01364-3
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发表时间：
2001-02-01
影响因子：
2.8
通讯作者：
Webb, G
中科院分区：
文献类型：
--
作者：
Fredriksen, PM;Veldtman, G;Webb, G
随着越来越多的先天性心脏病患者成年，需要更多有关结果的信息。心脏功能受损的最初迹象可能会在运动测试期间出现。本研究的目的是确定患有各种先天性心脏病的成人的最大摄氧量平均值。确定了来自 6 个主要诊断组的患者，包括房间隔缺损患者 (ASD，n = 93)、用 Mustard 手术矫正的问候动脉转位 (n = 84)、先天性矫正的大动脉转位 (CCTGA，n = 41)、法洛四联症 (n = 168)、Ebstein 异常 (n = 37) 和改良 Fontan 手术 (n = 52）。与健康受试者相比，所有年龄段的诊断组的最大摄氧量均减少。研究发现，自闭症谱系障碍患者的最大摄氧量随着年龄的增长而显着下降（p
As an increasing number of patients with congenital heart disease reach adulthood, more information is needed regarding outcomes. The first signs of impaired heart function may appear during exercise testing. The aim of the present study was to establish mean values for maximal oxygen uptake in adults with various congenital heart diseases. Patients from 6 major diagnostic groups were identified, including patients with atrial septal defect (ASD, n = 93), transposition of the greet arteries corrected with the Mustard procedure (n = 84), congenitally corrected transposition of the great arteries (CCTGA, n = 41), Tetralogy of Fallot (n = 168), Ebstein's anomaly (n = 37), and Modified Fontan procedure (n = 52). Diminished maximal oxygen uptake was found in all diagnostic groups across age compared with healthy subjects. A significant decrease in maximal oxygen uptake with aging was found in those with ASD (p