Risk factors for erysipelas of the leg (cellulitis): case-control study
Risk factors for erysipelas of the leg (cellulitis): case-control study
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DOI：
10.1136/bmj.318.7198.1591
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发表时间：
1999-06-12
影响因子：
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通讯作者：
Bastuji-Garin, S
中科院分区：
文献类型：
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作者：
Dupuy, A;Benchikhi, H;Bastuji-Garin, S
目的 评估腿部丹毒（蜂窝织炎）的危险因素。设计病例对照研究。在法国 7 个医院中心进行。受试者 167 名因腿部丹毒入院的患者和 294 名对照者。结果 在多变量分析中，皮肤屏障破坏（腿部溃疡、伤口、裂开的趾蹼擦烂、压疮或腿部皮肤病）（比值比23.8，95％置信区间10.7至52.5），淋巴水肿（71.2，5.6至908），静脉功能不全（2.9，1.0至8.7），腿部水肿（2.5，1.2至5.1）和超重（2.0，1.1至3.7）与丹毒独立相关腿的。没有观察到与糖尿病、酒精或吸烟之间的关联。趾蹼擦烂的人群归因风险为 61%。 结论 第一项病例对照研究强调了局部危险因素（主要是淋巴水肿和进入部位）在腿部丹毒中的主要作用：从公共卫生角度来看，应在腿部丹毒二级预防中评估趾蹼擦烂的检测和治疗。
Objective To assess risk factors for erysipelas of the leg (cellulitis).Design Case-control study.Setting 7 hospital centres in France.Subjects 167 patients admitted to hospital for erysipelas of the leg and 294 controls.Results In multivariate analysis, a disruption of the cutaneous barrier (leg ulcer, wound, fissurated toe-web intertrigo, pressure ulcer, or leg dermatosis) (odds ratio 23.8, 95% confidence interval 10.7 to 52.5), lymphoedema (71.2, 5.6 to 908), venous insufficiency (2.9, 1.0 to 8.7), leg oedema (2.5, 1.2 to 5.1) and being overweight (2.0, 1.1 to 3.7) were independently associated with erysipelas of the leg. No association was observed with diabetes, alcohol, or smoking. Population attributable risk for toe-web intertrigo was 61%.Conclusion This first case-control study highlights the major role of local risk factors (mainly lymphoedema and site of entry) in erysipelas of the leg: From a public health perspective, detecting and treating toe-web intertrigo should be evaluated in the secondary prevention of erysipelas of the leg.