Dietary energy density and diet variety as predictors of outcome in anorexia nervosa

Dietary energy density and diet variety as predictors of outcome in anorexia nervosa
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DOI:
10.1093/ajcn/87.4.810
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发表时间:
2008-04-01
影响因子:
7.1
通讯作者:
Walsh, B. Timothy
Walsh, B. Timothy
中科院分区:
医学1区
文献类型:
--
作者:
Schebendach, Janet E.;Mayer, Laurel E. S.;Walsh, B. Timothy

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背景:神经性厌食症(AN)是一种严重的精神疾病,具有显着的发病率和死亡率。成功的治疗可以使体重恢复,但累犯现象很常见,预计复发率高达 50%。维持健康饮食对于恢复过程至关重要,但尚未在 AN 患者中研究饮食与复发之间的关系。目的:本研究的目的是确定最近体重恢复的 AN 女性的饮食能量密度和饮食品种是否可以预测结果。设计:体重增加至体重指数(BMI;单位为 kg/m(2))为 20 后,47 名住院女性完成了 4 d 食物记录,从中得出平均饮食能量密度评分 (DEDS) 和平均饮食计算品种评分(DVS)。结果在研究结束时使用修改后的摩根-罗素标准确定,并分为“治疗成功”或“治疗失败”。通过使用学生 t 检验来分析数据。构建逻辑回归模型来评估 DEDS、DVS 和热量摄入对结果的影响。结果:各组在年龄、入院和体重恢复 BMI 或热量摄入的平均测量值上没有显着差异。然而,成功组的 DEDS 和 DVS 显着高于失败组。成功组和失败组分别平均随访 240 天和 170 天。在逻辑回归模型中,DEDS (P = 0.016) 和 DVS (P = 0.048) 但热量摄入 (P = 0.585) 可以显着预测结果。 结论:在最近体重恢复的 AN 女性中,较低的 DEDS 和 DVS 而不是热量摄入与不良结果相关。
Background: Anorexia nervosa (AN) is a serious psychiatric illness associated with significant morbidity and mortality. Successful treatment results in weight restoration, but recidivism is common, and the rate of relapse is estimated to be as high as 50%. Maintenance of a healthy diet is central to the recovery process, but the relation between diet and relapse has not been investigated in AN patients.Objective: The objective of the study was to determine whether diet energy density and diet variety in recently weight-restored women with AN predict outcome.Design: After gaining weight to a body mass index (BMI; in kg/m(2)) of 20, 47 hospitalized women completed 4-d food records, from which a mean diet energy density score (DEDS) and a mean diet variety score (DVS) were calculated. Outcome was determined at study end by using modified Morgan-Russell criteria, and it was dichotomized as "treatment success" or "treatment failure." Data were analyzed by using Student's t test. A logistic regression model was constructed to evaluate the effects of DEDS, DVS, and caloric intake on outcome.Results: Groups did not differ significantly in mean measures of age, admission and weight-restored BMI, or caloric intake. However, DEDS and DVS were significantly higher in the success group than in the failure group. The success and failure groups were followed for a mean of 240 and 170 d, respectively. In the logistic regression model, DEDS (P = 0.016) and DVS (P = 0.048) but not caloric intake (P = 0.585) significantly predicted outcome.Conclusion: In recently weight-restored women with AN, lower DEDS and DVS but not caloric intake were associated with poor outcome.