Research Progress in Cellular Pharmacokinetics
Research Progress in Cellular Pharmacokinetics
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发表时间：
2014
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通讯作者：
Ni Pin
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文献类型：
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作者：
Ni Pin
Classical pharmacokinetic studies based on the determination of plasma drug concentrations may not be sufficient to predict pharmacological response in vivo. Many drugs must pass through multiple biological barriers before they reach the intracellular target. There is a pressing need to expand classic pharmacokinetics from macroscopic plasma concentration of drugs to the cellular or subcellular levels. The progress in cellular pharmacokinetics was summarized. The overview and strategies regarding current knowledge about cellular pharmacokinetics were focused illustrating the successful applications of it in drug development, screening, and clinical application.
