Synthetic receptors for uronic acid salts based on bicyclic guanidinium and deoxycholic acid subunits
Synthetic receptors for uronic acid salts based on bicyclic guanidinium and deoxycholic acid subunits
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DOI：
10.1016/s0040-4020(97)00834-x
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发表时间：
1997-09-22
期刊：
影响因子：
2.1
通讯作者：
deMendoza, J
中科院分区：
文献类型：
--
作者：
Segura, M;Alcazar, V;deMendoza, J
以手性双环胍单元和去氧胆酸衍生物为基础，制备了四种糖醛酸盐受体。葡萄糖酸盐和半乳糖酸盐在CD3CN/CDCl3中的结合常数为3200 ~ 7000 M-1。含去脱氧胆碱的受体对葡萄糖醛酸盐更有效，选择性适中。1997爱思唯尔科学有限公司
Four receptors for uronic acid salts have been prepared using a chiral bicyclic guanidinium unit and deoxycholic acid derivatives as building blocks. Binding constants in CD3CN/CDCl3 ranged from 3200 to 7000 M-1 for glucuronate and galacturonate salts. Nordeoxycholic-containing receptors were found more efficient and moderately selective for glucuronic salts. (C) 1997 Elsevier Science Ltd.