Wound recurrence following laparoscopic colon cancer resection
Wound recurrence following laparoscopic colon cancer resection
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腹腔镜结肠癌切除术后伤口复发
DOI：
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发表时间：
1996
影响因子：
3.9
通讯作者：
R. Beart
中科院分区：
文献类型：
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作者：
P. Vukasin;A. Ortega;F. Greene;G. Steele;A. Simons;G. Anthone;L. Weston;R. Beart
多个病例报告表明，腹腔镜结肠癌切除术可能会改变癌症复发的模式或发生率。所有的报道都缺乏一个重要的分母来评估手术伤口复发的发生率。我们假设腹腔镜结肠癌切除术不会增加伤口复发率。方法：1992年，在美国结肠直肠外科学会、美国外科学会和美国胃肠内镜外科学会的支持下，开展了一项前瞻性登记。接受腹腔镜结肠切除术的患者自愿进入并随访至1995年6月。由主治医生评估复发情况并向登记处报告。结果：共有504名接受癌症治疗的患者在登记中被确定。493例可评估患者中的480例（97.4%）获得了至少一年的随访。5例（1.1%）患者伤口复发。18例（3.8%）患者复发情况不明。结论：创面复发率低。虽然随访时间有限，但从以往的研究来看，80%的复发应该发生在一年内。鉴于II期研究的局限性，复发率低的假设得到了支持。然而，需要前瞻性随机试验来确定腹腔镜或开放式结直肠癌切除术后伤口复发率是否存在差异。
INTRODUCTION: Multiple case reports have suggested that laparoscopic resection of colon cancer may alter the pattern or incidence of cancer recurrence. All reports lack a significant denominator to evaluate the incidence of surgical wound recurrence. We hypothesized that wound recurrence incidence is not increased by laparoscopic resection of colon cancer. METHODS: A prospective registry was initiated under the auspices of The American Society of Ccolon and Rectal Surgeons, American College of Surgeons, and Society of American Gastrointestinal Endoscopic Surgeons in 1992. Patients having laparoscopic colon resection were voluntarily entered and followed until June 1995. Recurrences were evaluated by the primary surgeon and reported to the registry. RESULTS: A total of 504 patients treated for cancer were identified in the registry. A minimum follow-up of one year was obtained for 480 of 493 evaluable patients (97.4 percent). Wound recurrence was identified in five patients (1.1 percent). Recurrence status was unknown in 18 patients (3.8 percent). CONCLUSION: Wound recurrence rates appear to be low. Although length of follow-up is limited, patterns of recurrence from previous studies suggest that 80 percent of recurrences should have occurred within one year. Given the limitations of a Phase II study, the hypothesis that recurrence rate is low is supported. However, prospective randomized trials are needed to establish if any difference in wound recurrence rates after laparoscopic or open resection of colorectal cancer exists.