Cortical network for vibrotactile attention: A fMRI study
Cortical network for vibrotactile attention: A fMRI study
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DOI：
10.1002/hbm.20384
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发表时间：
2008-02-01
影响因子：
4.8
通讯作者：
McLaren, Donald G.
中科院分区：
文献类型：
--
作者：
Burton, Harold;Sinclair, Robert J.;McLaren, Donald G.
我们使用功能磁共振成像来识别触觉注意力任务期间激活的大脑区域。受试者检测到的间隔包含更高的振动触觉频率或更长的持续时间的目标刺激。属性被选择性地或中性地提示。一个控制向后计数任务包括并发的，但不相关的相应的振动触觉刺激。平均F-统计图，参与者连接图，估计的时间过程中使用的数据映射到一个标准的平均表面地图集（帕尔斯B12）的组分析。重复测量，随机效应MANOVA检查血氧水平依赖性（BOLD）信号调制差异的任务在定义的区域，其中显着的反应发生在至少50%的组。在对侧顶叶鳃盖OP 1、BA 4指区、额叶眼区、背侧前运动区、BA 7前后区和双侧上级颞叶沟皮层（BA 22）、腹侧前运动区、辅助运动区和额叶鳃盖/额叶皮层中的至少一个触觉注意任务中，BOLD反应增加大于0.1%。同样的任务抑制了同侧OP 4的活动。BA 22 ROI在中性提示期间显示较大的响应。控制任务抑制BOLD在同侧OPI和OP 4和双侧BA 40，但显着增强的反应，在背侧顶额区相比，触觉注意任务。在选择性提示频率和持续时间任务之间没有发现区域差异。触觉注意效应在OPI中最为突出。后顶叶反应可能反映了向后计数所需的视觉注意，而额叶区域可能与目标导向行为时，识别目标刺激。(c)2007 Wiley-Liss，Inc.
We used fMRI to identify brain areas activated during tactile attention tasks. Participants detected the interval containing target stimulation of higher vibrotactile frequency or longer duration. Attributes were selectively or neutrally cued. A control backwards-counting task included concurrent, but irrelevant corresponding vibrotactile stimulation. Group analyses of average F-statistic maps, participant conjunction maps, and estimated time courses utilized data mapped to a standard average surface atlas (PALS B12). Repeated-measures, random-effects MANOVA examined blood oxygenation level-dependent (BOLD) signal modulation differences amongst tasks in defined regions, where significant responses occurred in at least 50% of the group. Greater than 0.1% increase in BOLD responses were found during at least one of the tactile attention tasks in contralateral parietal opercular OP1, BA 4 finger region, frontal eye field, dorsal premotor, anterior and posterior BA 7, and bilaterally in superior temporal sulcal cortex (BA 22), ventral premotor, supplementary motor area, and frontal operculum/insula. The same tasks suppressed activity in ipsilateral OP4. The BA 22 ROI showed larger responses during neutral cuing. The control task suppressed BOLD in ipsilateral OPI and OP4 and bilaterally in BA 40, but significantly enhanced responses in dorsal parietal-frontal regions compared with tactile attention tasks. No regional differences were found between selectively cued frequency and duration tasks. Tactile attention effects were most prominent in OPI. Posterior parietal responses possibly reflected the visual attention required for backwards-counting, whereas the frontal regions potentially related to goal-directed behavior when identifying target stimulation. (c) 2007 Wiley-Liss, Inc.