Molecular identification of an invasive gingival bacterial community

Molecular identification of an invasive gingival bacterial community
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DOI:
10.1086/430824
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发表时间:
2005-07-01
影响因子:
11.8
通讯作者:
Myerson, D
Myerson, D
中科院分区:
医学1区
文献类型:
--
作者:
Fredricks, DN;Schubert, MM;Myerson, D

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一名妇女与中性粒细胞减少症发展牙龈增生。活检显示侵入牙龈组织与垫的丝状生物,和聚合酶链反应和荧光原位杂交分子分析显示,Capnocytophaga sputigena,Leptotrichia物种,和核梭杆菌。口腔细菌植物群可导致免疫功能低下患者的侵袭性牙龈疾病伴增生。
A woman with neutropenia developed gingival hyperplasia. Biopsy showed invasion of gingival tissue with mats of filamentous organisms, and molecular analysis by polymerase chain reaction and fluorescence in situ hybridization revealed Capnocytophaga sputigena, Leptotrichia species, and Fuso-bacterium nucleatum. Oral bacterial flora may cause invasive gingival disease with hyperplasia in immunocompromised patients.