Demographics and occurrence of oral and pharyngeal cancers - The outcomes, the trends, the challenge

Demographics and occurrence of oral and pharyngeal cancers - The outcomes, the trends, the challenge
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DOI:
10.14219/jada.archive.2001.0382
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发表时间:
2001-11-01
影响因子:
3.9
通讯作者:
Silverman, S
Silverman, S
中科院分区:
医学3区
文献类型:
--
作者:
Silverman, S

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概况.本文总结了目前口腔咽癌的发病趋势、死亡率和生存率。作者回顾了有关口腔和咽癌的这些方面的数据和文献,包括从1973年至1998年收集的癌症研究所的监测,流行病学和最终结果计划的数据。美国口腔和咽部疾病的发生率保持不变,每年确诊约30,000例新病例。尽管手术和放射治疗取得了进展,但五年生存率没有明显改善,仍然保持在50%左右。在过去的三十年中,早期局部病变的检测没有显著改善。有一个小的趋势,在年轻的诊断年龄增加的妇女。流行病学的基础上,它似乎是最重要的方法,以减少发病率和ally与口腔癌是增加早期发现局部病变结合适当的治疗。同时,积极的咨询是至关重要的,以防止使用和鼓励停止烟草和酒精的使用。关于口腔和咽癌的专业和公众教育需要改进,临床医生必须强调需要并进行常规或癌症检查,以促进早期诊断和治疗。
Overview. This article summarizes current trends in the occurrence of, mortality rates associated with and rates of survival of oral and pharyngeal cancer.Methods. The author reviewed relevant data and literature on these aspects of oral and pharyngeal cancer, including data from the Cancer Institute's Surveillance, Epidemiology and End Results program collected from 1973 to 1998.Results. The occurrence of oral and pharyngeal in the United States remains constant, at about 30,000 new cases diagnosed each year. There has been no marked improvement in the five-year survival rates, which remain at about 50 percent,despite advances in surgery and radiation. Detection, of early, localized lesions has not improved significantly during the past three decades. There is a minor trend toward a younger age at diagnosis increase among women.Conclusions. On the basis of epidemiologic it appears that the most important approach to decreasing morbidity and ali y associated with oral cancer is increasing early detection of localized lesions combined with appropriate treatment Concomitantly, aggressive counseling is vital to prevent use and encourage cessation of tobacco and alcohol use.Clinical Implications. Professional and public education about oral and pharyngeal cancer needs to be improved, and clinicians must emphasize the need for and perform routine or cancer examinations to promote early diagnosis and treatment.