Effect of carbon nanotube and aluminum oxide addition on plasma-sprayed hydroxyapatite coating's mechanical properties and biocompatibility
Effect of carbon nanotube and aluminum oxide addition on plasma-sprayed hydroxyapatite coating's mechanical properties and biocompatibility
复制标题
DOI：
10.1016/j.msec.2009.05.001
复制
发表时间：
2009-08-31
影响因子：
7.9
通讯作者：
Agarwal, Arvind
中科院分区：
文献类型：
--
作者：
Tercero, Jorge E.;Namin, Shabnam;Agarwal, Arvind
采用等离子喷涂技术制备了碳纳米管（CNTs）/氧化铝（Al 2 O3）复合羟基磷灰石（HA）生物陶瓷涂层。HA的断裂韧性-20 wt.%与HA涂层相比，Al 2 O3提高了158%，而HA-18.4wt.% Al 2 O3 -1.6重量% CNT显示出300%的改善。碳纳米管通过钢筋机制提供增强。人纤维成骨细胞生长研究表明，涂层的生物相容性保持不变，因为Al 2 O3保留了其生物惰性和CNT，其生物活性，在复合涂层内。复合涂层对成骨细胞的附着力较低，但增殖率较高，这归因于表面粗糙度。建立了涂层组成、生物相容性和力学性能之间的优化关系，以预测最适合骨科植入物的涂层材料。HA-Al_2 O_3-CNT复合涂层在保持生物相容性的同时，力学性能得到了极大的改善。(C)2009 Elsevier B. V.保留所有权利。
This study reports on the synthesis of novel bioceramic composite coating of hydroxyapatite (HA) reinforced with carbon nanotubes (CNTs) and aluminum oxide (Al2O3) using plasma spray technique. Fracture toughness of HA-20 wt.% Al2O3 improved by 158% as compared to HA coating whereas HA-18.4 wt.% Al2O3-1.6 wt.% CNT showed an improvement of 300%. Carbon nanotubes provided reinforcement via rebar mechanism. Human fiber osteoblast cell-growth studies showed that biocompatibility of the coating remained unaltered, as Al2O3 retained its bio-inertness and CNT, its bioactivity, within the composite coatings. Composite coating showed lower attachment, but higher proliferation rate, for the osteoblast cells, which has been attributed to the surface roughness. An optimized relation between coating composition, its biocompatibility and mechanical properties was established to predict the most suited coating material for orthopedic implants. HA-Al2O3-CNT composite coating displayed most improved mechanical properties while retaining its biocompatibility. (C) 2009 Elsevier B.V. All rights reserved.