Neuromotor speech deficits in children and adults with spina bifida and hydrocephalus
Neuromotor speech deficits in children and adults with spina bifida and hydrocephalus
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DOI：
10.1006/brln.2001.2620
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发表时间：
2002-03-01
影响因子：
2.5
通讯作者：
Spiegler, BJ
中科院分区：
文献类型：
--
作者：
Huber-Okrainec, J;Dennis, M;Spiegler, BJ
获得性小脑病变与运动性语言障碍有关。脊柱裂伴脑积水是一种神经发育障碍，涉及小脑的显著畸形。由40名SBH儿童和成人及其40名年龄匹配的对照组制作的录像叙述被编码为三种运动言语缺陷：流利性障碍，共济失调性构音障碍（发音不准确，韵律过度和发音韵律不足）（Brown，Darley，Aronson，1970; Darley，Aronson，& Brown，1969 a）和语速。SBH患者的运动性言语障碍比对照组多。语言流畅障碍与实际年龄和SBH之间的相互作用有关。言语率与实足年龄和SBH独立相关。共济失调性构音障碍与SBH的生物学相关，并与物理表型（脊髓病变水平）和病史（分流翻修次数）相关。这些数据表明，小脑的发育性和后天性病变会破坏运动言语，并增加小脑在运动技能（包括言语）自动化中的发育作用。(C)2002年爱思唯尔科学（美国）。
Acquired cerebellar lesions are associated with motor speech deficits. Spina bifida with hydrocephalus (SBH) is a neurodevelopmental disorder that involves significant dysmorphology of the cerebellum. Videotaped narratives produced by 40 children and adults with SBH and their 40 age-matched controls were coded for three motor speech deficits: dysfluency, ataxic dysarthria (articulatory inaccuracy, prosodic excess, and phonatory-prosodic insufficiency) (Brown, Darley, Aronson, 1970; Darley, Aronson, & Brown, 1969a), and speech rate. Individuals with SBH had more motor speech deficits than controls. Dysfluency was related to an interaction between chronological age and SBH. Speech rate was related independently to chronological age and SBH. Ataxic dysarthria was related to the biology of SBH, and was associated with both physical phenotype (level of spinal cord lesion) and medical history (number of shunt revisions). The data show that developmental as well as acquired lesions of the cerebellum disrupt motor speech, and add to the developmental role of the cerebellum in the automatization of motor skills, including speech. (C) 2002 Elsevier Science (USA).