Physical activity, lung function, and sleep outcomes in urban children with asthma.

Physical activity, lung function, and sleep outcomes in urban children with asthma.
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城市哮喘儿童的体力活动、肺功能和睡眠结果。

DOI:
10.1002/ppul.25397
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发表时间:
2021-07
影响因子:
3.1
通讯作者:
Koinis-Mitchell D
Koinis-Mitchell D
中科院分区:
医学3区
文献类型:
--
作者:
Powers KE;Jelalian E;Dunsiger S;Farrow M;Miranda LG;Mitchell P;Kopel S;Koinis-Mitchell D

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研究(1)在城市哮喘儿童样本中,每天体力活动(PA)水平和/或肺功能(FEV1)的下降是否预示着哮喘的恶化,以及(2)在这一组中,睡眠觉醒次数与白天PA下降之间的关系。在这个7-9岁患有持续性哮喘的城市儿童样本(N=147)中,客观方法通过手持肺活量计评估肺功能和通过加速计评估中等强度体力活动(MVPA),作为更大的5年研究的一部分,在每年秋季和初冬的4周时间内进行测量。在整个样本中,PA和肺功能之间的显著关联被注意到,每天MVPA下降越多,恶化的几率就越低。种族差异表明,这种关联也只在拉丁裔儿童中显著(OR=0.98;95%CI:0.97-0.99)。睡眠唤醒的次数越多,每天的MVPA下降幅度就越大,只有在拉丁裔中才是如此(p=0.05)。结果表明,MVPA的下降可能有助于降低病情恶化的风险。MVPA下降的原因需要在这一组中进一步探讨。哮喘儿童可能避免或害怕参与PA,或者可能面临影响PA模式的早期症状,这可能会将病情恶化的风险降至最低。结果还表明,夜间中断的原因可能需要在进一步的研究或干预中有针对性,因为它们可能有助于在这一高危人群中避免PA。
To examine (1) whether daily declines in physical activity (PA) level and/or in lung function (FEV1) predict an asthma exacerbation in a sample of urban children with asthma, and (2) the association between number of sleep awakenings and decline in daytime PA in this group. In this sample of urban children aged 7–9 years with persistent asthma (N=147), objective methods assessing lung function via a handheld spirometer and moderate-vigorous physical activity (MVPA) via accelerometry were measured over a 4-week period during the fall and early winter of each year as part of a larger 5-year study. In the entire sample, a significant association between PA and lung function was noted such that a greater decline in daily MVPA was associated with lower odds of exacerbation. Ethnic group differences showed that this association was also significant only among Latino children (OR=0.98; 95% CI:0.97–0.99). A greater number of sleep awakenings were associated with greater declines in daily MVPA among Latinos only (p=0.05). Results suggest that declining MVPA may contribute to lower risk for an exacerbation. Reasons for declining MVPA need to be further explored in this group. Children with asthma may avoid or be fearful of engaging in PA or may face early symptoms which influence patterns of PA, and this may minimize risk for an exacerbation. Results also suggest reasons for nighttime disruptions may need to be targeted in further research or interventions as they can contribute to PA avoidance in this high-risk group.
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