Maternal Depressive Symptoms during Pregnancy, and Newborn Irritability
Maternal Depressive Symptoms during Pregnancy, and Newborn Irritability
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母亲孕期抑郁症状和新生儿烦躁
DOI：
10.1097/00004703-199008000-00006
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发表时间：
1990
影响因子：
2.4
通讯作者：
H. Cabral
中科院分区：
文献类型：
--
作者：
B. Zuckerman;H. Bauchner;S. Parker;H. Cabral
母亲抑郁与儿童的一系列不良后果有关，包括产后3个月母婴互动不良。这项研究的目的是确定母亲怀孕期间的抑郁症状是否与神经学和适应能力量表测量的新生儿神经行为功能有关。研究人群由1123名母亲和她们的足月婴儿组成，她们参与了一项关于孕产妇健康和婴儿结局的更大规模的研究。妇女在怀孕期间接受了流行病学研究中心抑郁症(CES-D)问卷调查。随后，儿科医生对他们的婴儿进行了评估，对他们的CES-D得分视而不见。CES-D评分与悲伤和过度哭泣有关(p<；0.01)。母亲的CES-D得分越高，婴儿就越有可能悲伤或过度哭泣。CES-D得分在第90个百分位数的母亲生下悲伤新生儿的可能性是CES-D得分在第10个百分位数的母亲的2.6倍(95%C.I.=1.54，4.23)。当控制了潜在的混杂变量，如吸烟、酒精、大麻和可卡因使用、体重增加不佳、收入、出生体重和其他药物使用时，CES-D评分与新生儿悲伤和过度哭泣的关系保持不变。这项研究的结果表明，儿童早期问题和母亲抑郁症状之间的关系可能是从怀孕期间抑郁症状开始的序列的一部分。
Maternal depression is associated with a wide range of adverse outcomes for children, including poor mother-infant interactions at 3 months post-partum. The aim of this study is to determine whether maternal depressive symptoms during pregnancy are associated with neonatal neurobehavioral functioning, as measured by the Neurologic and Adaptive Capacity Scale. The study population consists of 1,123 mothers and their term infants who were participants in a larger study of maternal health and infant outcomes. Women were administered the Center for Epidemiologic Studies-Depression (CES-D) questionnaire for depressive symptoms during their pregnancy. Their infants were subsequently assessed by a pediatrician blind to their CES-D scores. The CES-D score was associated with unconsolability and excessive crying (p < 0.01). The higher the mother's CES-D score, the more likely it was that the infant would be unconsolable or cry excessively. Mothers with CES-D scores at the 90th percentile were 2.6 times more likely to have unconsolable newborns, compared with women with CES-D scores at the 10th percentile (95% C.I. = 1.54, 4.23). When potentially confounding variables, such as cigarette smoking, alcohol, marijuana, and cocaine use, poor weight gain, income, birth weight, and other drug use, were controlled, the relationship between CES-D score and newborn unconsolability and excessive crying remain unchanged. The results of this study suggest that the relationship between early childhood problems and maternal depressive symptoms may be part of a sequence that starts with depressive symptoms during pregnancy.